Table 1 Baseline characteristics by treatment group among the PAADRN participants (N = 7,749)

 Age, mean (SD)

66.5 (8.4)

66.7 (8.2)

0.246¹

 Women, N (%)

3,259 (83.6)

3,230 (83.9)

0.750²

 White, N (%)

2,981 (76.5)

2,954 (76.7)

0.699²

 Black, N (%)

842 (21.6)

814 (21.1)

 Other, N (%)

75 (1.9)

83 (2.2)

 Some high school, N (%)

161 (4.2)

140 (3.7)

0.749²

 Completed high school, N (%)

819 (21.2)

836 (21.9)

 Some college, N (%)

1,290 (33.4)

1,269 (33.2)

 Completed college, N (%)

785 (20.3)

762 (19.9)

 Graduate school, N (%)

809 (20.9)

814 (21.3)

 COPD, N (%)

259 (6.7)

265 (6.9)

0.680²

 Depression, N (%)

902 (23.2)

885 (23.0)

0.878²

 Prostate cancer, N (%)

117 (18.3)

88 (14.2)

0.048²

 Breast cancer, N (%)

416 (10.7)

612 (15.9)

<0.001²

 Current smoker, N (%)

295 (7.6)

295 (7.7)

0.873²

 Past smoker, N (%)

1,478 (37.9)

1,388 (36.1)

0.095²

 Current alcohol user, N (%)

1,768 (45.4)

1,808 (47.0)

0.157²

 Excellent, N (%)

445 (11.4)

494 (12.8)

0.329²

 Very Good, N (%)

1,443 (37.1)

1,373 (35.7)

 Good, N (%)

1,280 (32.9)

1,253 (32.6)

 Fair, N (%)

571 (14.7)

566 (14.7)

 Poor, N (%)

150 (3.9)

159 (4.1)

 Prior DXA, N (%)

2,606 (66.9)

2,590 (67.3)

0.719²

 History of OP, N (%)

794 (20.6)

909 (23.8)

0.001²

 History of OP treatment, N (%)

1,438 (36.9)

1,502 (39.0)

0.055²

 Glucocorticoids Use, N (%)

593 (15.2)

576 (15.0)

0.753²

 Normal, N (%)

1,133 (29.1)

990 (25.7)

0.001²

 Low BMD, N (%)

2,052 (52.6)

2,066 (53.6)

 Osteoporosis, N (%)

713 (18.3)

795 (20.6)

 Lowest T-Score, mean (SD)

-1.62 (1.1)

-1.55 (1.1)

0.002¹

 10-year Fracture Risk (FRAX), mean (SD)

12.0 (9.2)

12.3 (9.1)

0.101¹