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Table 5 Potential predictors at time of diagnosis for inflammatory infiltrates recorded in pathology reports

From: The effect of clinical features and glucocorticoids on biopsy findings in giant cell arteritis

Feature

Odds ratio

95 % CI

p

Sex (female vs male)

1.93

0.91–4.06

0.09

Age (per year)

1.01

0.97–1.05

0.61

Time from glucocorticoid treatment to TAB (per day)

1.01

0.96–1.07

0.66

Current smoking vs non-current smokingc

0.65

0.30–1.41

0.27

Ever smoking vs never smokingc

0.62

0.22–1.75

0.37

ESR (per mm/h)

1.01

1.00–1.03

0.05

CRP (per mg/l)

1.01

1.00–1.02

0.01

Time from glucocorticoid treatment to TAB

  < 1 dayd

3.30

1.15–9.49

0.03

 1-3 days

1.00 (reference)

  

 4-6 days

1.90

0.74–4.62

0.19

 7-28 days

1.27

0.41–3.92

0.68

ESR (mm/h) a,c

 Quartile 1 (20–61)

1.00 (reference)

  

 Quartile 2 (62–79)

0.51

0.19–1.36

0.18

 Quartile 3 (80–99)

1.14

0.43–3.01

0.80

 Quartile 4 (100–150)

3.13

0.90–10.90

0.07

CRP (mg/l) b,c

 Quartile 1 (4–56)

1.00 (reference)

  

 Quartile 2 (57–98)

2.89

0.94–8.86

0.06

 Quartile 3 (99–142)

4.64

1.33–16.23

0.02

 Quartile 4 (143–478)

3.60

1.11–11.62

0.03

  1. TAB temporal artery biopsy, ESR erythrocyte sedimentation rate, CRP C-reactive protein, CI confidence interval
  2. a p for trend 0.03
  3. b p for trend 0.01
  4. cAvailable data: ESR from 171 patients; CRP 136 patients; current smoking at diagnosis 98 patients; ever smoking 135 patients
  5. dIncludes individuals biopsied before start of glucocorticoid treatment