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Table 1 Baseline characteristics of rheumatoid arthritis patients by response to anti-TNF therapy at 6 months

From: Variations in the metabolome in response to disease activity of rheumatoid arthritis

 

Good responders (n = 100)

Non-responders (n = 40)

P-value

Age, years (mean ± SD)

50 ± 14

57 ± 13

0.44

Female (%)

76 (76)

31 (77.5)

1.00

Disease duration (months, range)

9 (3.3–15.3)

10 (3.7–12.8)

0.54

Infliximab (%)

13 (13)

7 (17)

0.64

Adalimumab (%)

29 (29)

17 (43)

0.32

Etanercept (%)

58 (58)

16 (40)

0.82

DAS-28 M0 (Mean ± SD)

4.8 ± 0.9

5.0 ± 1.2

-

DAS-28 M6 (Mean ± SD)

2.2 ± 0.6

4.8 ± 1.2

-

RF positivity (%)

77.4

70

0.25

ACPA positivity (%)

75

62

0.18

ERS (mm/h)

32 ± 25

35 ± 23

0.37

CRP (mg/l)

17 ± 19

21 ± 18

0.45

Bone erosion (%)

38

31

0.37

  1. RF rheumatoid factor, ACPA anticitrullinated protein antibodies, ERS erythrocyte sedimentation rate, CRP C-reactive protein