Table 2 The proportion of patients in CDAI/SDAI/DAS28 remission, low activity, moderate activity and high activity states at 0, 6 and 12 weeks. CDAI: Clinical Disease Activity Index; SDAI: Simplified Disease Activity Index; DAS28: Disease Activity Score in 28 joints (using ESR)
Remission score | Baseline No. (%) | 6 weeks No. (%) | 12 weeks No. (%) | Early (0–6 weeks) vs. Late (6–12 weeks) (p) | |
|---|---|---|---|---|---|
CDAI | N | 102 | 96 | 89 | |
Remission ( ≤ 2.8) | 0 (0.0) | 16 (16.7) | 17 (19.1) | 0.0002 | |
Low Activity (2.9–10.0) | 9 (8.8) | 25 (26.0) | 48 (53.9) | 0.15 | |
Moderate Activity (10.1–22.0) | 26 (25.5) | 37 (38.5) | 21 (23.6) | ||
High Activity ( > 22) | 67 (65.7) | 18 (18.8) | 3 (3.4) | ||
SDAI | N | 97 | 58 | 37 | |
Remission ( ≤ 3.3) | 0 (0.0) | 4 (6.9) | 3 (8.1) | ||
Low Activity (3.4–11.0) | 3 (3.1) | 13 (22.4) | 16 (43.2) | 0.08 | |
Moderate Activity (11.1–26) | 15 (15.5) | 19 (32.8) | 13 (35.1) | ||
High Activity ( ≥ 26) | 79 (81.4) | 22 (37.9) | 5 (13.5) | ||
DAS28 | N | 94 | 85 | 76 | |
Remission ( ≤ 2.4) | 2 (2.1) | 22 (25.9) | 23 (30.3) | 0.00002 | |
Low Activity (2.5–3.6) | 9 (9.6) | 28 (32.9) | 33 (43.4) | 0.41 | |
Moderate Activity (3.7–5.5) | 40 (42.6) | 29 (34.1) | 19 (25.0) | ||
High Activity ( ≥ 5.5) | 43 (45.7) | 6 (7.1) | 1 (1.3) | ||