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Table 2 Changes of disease activity and HAQ-DI in EST and NEW patients (median (25th and 75th percentile))

From: Validity of data collected in BIOREG, the Austrian register for biological treatment in rheumatology: current practice of bDMARD therapy in rheumatoid arthritis in Austria

 

EST (n = 284)

NEW (n = 62)

baseline

after 1 year

baseline

after 1 year

DAS28

2.67 (1.99, 3.70)

2.58 (1.80, 3.45)

4.46 (3.77, 5.35)

2.43 (1.54, 3.57)

DAS28 Diff

 

0.18 (-0.47, 0.87)

 

1.92 (0.65, 2.99)

RADAI-5

2.6 (1.2, 4.4)

2.2 (1.0, 4.0)

4.4 (3.2, 6.2)

2.4 (1.2, 3.8)

RADAI-5 Diff

 

0.2 (-0.5, 1.2)

 

2.0 (0.6, 3.4)

HAQ

0.63 (0.13, 1.19)

0.63 (0.13, 1.13)

1.00 (0.63, 1.38)

0.50 (0.13, 1.25)

HAQ Diff

 

0.00 (-0.13, 0.25)

 

0.38 (0.00, 0.63)

  1. Abbreviations: DAS28 Disease Activity Score using ESR out of 28 joints, DIFF Difference to baseline after 1 year follow up, ESR Erythrocyte Sedimentation Rate, EST pts with established bDMARD treatment before inclusion in BIOREG of whom a full data set as described is viable, HAQ-DI Health Assessment Questionnaire Disability Index, N number of pts, NEW pts included in BIOREG with start of biologic treatment ± 30 days of whom a full data set as described is viable, PTS patients, RADAI-5 Rheumatoid Arthritis Disease Activity Index-5