From: Systematic review of non-surgical treatments for early Dupuytren’s disease
Author (year) treatment | Total cohort of DD patients (hands) | Number of patients (hands) with early DD | Study type | Level of evidence (OCEBM) Prospective (P) Retrospective (R) Not stated (N) | Outcome measure | Results | Recurrence | Adverse events | ||
---|---|---|---|---|---|---|---|---|---|---|
Improved | No change | Deteriorated | ||||||||
Markham (1980) [40], Ultrasound | 8 (9 hands) | 3 (4 hands) | Case series | 4 (P) | Digital joint extension in degrees (n = 4) | 2 | (2 had no extension deficit at baseline) | 0 | None | Not reported |
Clinical observation (n = 2) | 1 patient (2 hands) | |||||||||
Hand span (n = 4) | 2 | 2 | ||||||||
Grip strength (n = 4) | 4 | |||||||||
Ball (2002) [41], Splinting | 6 (7 hands) | 5 (6 hands) | Case series | 4 (P) | Active digital joint extension in degrees | 4 patients (5 hands) | 1 patient (1 hand) | 0 | None at 2 years | Not reported |
Larocerie-Salgado, (2012) [42], Splinting | 13 (13 hands) | 2 | Case series | 4 (P) | Digital joint extension in degrees | 2 patients | 0 | 0 | Not reported | Not reported |
Christie (2012) [43], Frictional massage, (Treatment hand) | 1 (2 hands) | 1 (2 hands) | Case study | 5 (P) | Active digital joint extension in degrees | 1 hand (2 digits) | 0 | 0 | Not reported | Not reported |
(Control hand) | 0 | 0 | 1 hand (2 digits) | |||||||
Onat (2013) [44], Heat, splinting, stretching | 3 | 2 | Case series | 5 (N) | Degrees of digital motion | 2 | 0 | 0 | Not reported | Not reported |