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Table 2 Reasons for discontinuation of TNF inhibitors, N (%)

From: Drug retention and safety of TNF inhibitors in elderly patients with rheumatoid arthritis

 

Total (n = 429)

Elderly patients (n = 107)

Younger patients (n = 322)

p value

Number of discontinuations

167 (38.9)

35 (32.7)

132 (41.0)

0.16

Reason for discontinuation

   

0.43

 Adverse effect

44 (26.4)

12 (34.3)

32 (24.2)

 

 Ineffectiveness

64 (38.3)

9 (25.7)

55 (41.7)

 

 Patient need

37 (22.2)

9 (25.7)

28 (21.2)

 

 Good effectiveness

7 (4.2)

2 (5.7)

5 (3.8)

 

 Economic problem

3 (1.8)

1 (2.9)

2 (1.5)

 

 Operation or hospitalization

4 (2.4)

1 (2.9)

3 (2.3)

 

 Othera

3 (1.8)

1 (2.9)

2 (1.5)

 

 Unknown

5 (3.0)

-

5 (3.8)

 
  1. aOther reasons include mobility impaired, preparation for pregnancy, and dental treatment
  2. Bold means statistical significant at the p < 0.05