From: Drug retention and safety of TNF inhibitors in elderly patients with rheumatoid arthritis
 | Total (n = 429) | Elderly patients (n = 107) | Younger patients (n = 322) | p value |
---|---|---|---|---|
Number of discontinuations | 167 (38.9) | 35 (32.7) | 132 (41.0) | 0.16 |
Reason for discontinuation | Â | Â | Â | 0.43 |
 Adverse effect | 44 (26.4) | 12 (34.3) | 32 (24.2) |  |
 Ineffectiveness | 64 (38.3) | 9 (25.7) | 55 (41.7) |  |
 Patient need | 37 (22.2) | 9 (25.7) | 28 (21.2) |  |
 Good effectiveness | 7 (4.2) | 2 (5.7) | 5 (3.8) |  |
 Economic problem | 3 (1.8) | 1 (2.9) | 2 (1.5) |  |
 Operation or hospitalization | 4 (2.4) | 1 (2.9) | 3 (2.3) |  |
 Othera | 3 (1.8) | 1 (2.9) | 2 (1.5) |  |
 Unknown | 5 (3.0) | - | 5 (3.8) |  |