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Table 2 Crude and age-adjusted association between selected characteristics and disease severity at diagnosis

From: Factors associated with diagnostic stage of hip osteoarthritis due to acetabular dysplasia among Japanese female patients: a cross-sectional study

Characteristics Disease stage at OA diagnosis, n (%) Univariate Age-adjusted
Pre OA Initial Advanced Terminal OR (95 % CI) OR (95 % CI)
Age (years)       
20–49 30 (70) 24 (50) 20 (21) 16 (11) 1.00  
50–57 5 (12) 11 (23) 37 (39) 29 (19) 4.26 (2.42–7.51)  
58–66 7 (16) 8 (17) 18 (19) 45 (30) 7.83 (4.29–14.3)  
67+ 1 (2) 5 (10) 20 (21) 60 (40) 15.1 (8.02–28.4)  
      (Trend P < 0.01)  
Height (cm)       
<150.0 4 (9) 4 (8) 22 (23) 46 (31) 1.00 1.00
150.0–153.9 5 (12) 14 (29) 29 (31) 48 (32) 0.65 (0.36–1.17) 0.67 (0.37–1.24)
154.0–157.9 18 (42) 9 (19) 20 (21) 27 (18) 0.30 (0.16–0.55) 0.46 (0.24–0.88)
158.0+ 16 (37) 21 (44) 24 (25) 29 (19) 0.27 (0.15–0.49) 0.53 (0.28–0.99)
      (Trend P < 0.01) (Trend P = 0.04)
Weight at age 20 (kg)      
<46.0 7 (17) 12 (26) 23 (25) 39 (28) 1.00 1.00
46.0–49.9 6 (14) 11 (24) 25 (27) 32 (23) 0.89 (0.50–1.61) 0.89 (0.48–1.63)
50.0–54.9 15 (36) 14 (30) 25 (27) 35 (25) 0.65 (0.38–1.14) 0.68 (0.38–1.22)
55.0+ 14 (33) 9 (20) 18 (20) 35 (25) 0.78 (0.44–1.40) 0.93 (0.51–1.71)
      (Trend P = 0.24) (Trend P = 0.59)
Weight change since age 20 (kg)     
<−2 10 (24) 7 (15) 11 (12) 34 (24) 2.14 (1.15–3.96) 1.87 (0.98–3.55)
±2 16 (38) 14 (30) 23 (25) 26 (18) 1.00 1.00
>2 16 (38) 25 (54) 57 (63) 81 (57) 1.86 (1.15–3.02) 1.80 (1.08–2.98)
      (Trend P = 0.71) (Trend P = 0.56)
Weight at diagnosis (kg)     
<48.5 11 (26) 10 (21) 25 (26) 38 (25) 1.00 1.00
48.5–53.4 10 (23) 16 (33) 19 (20) 43 (29) 1.04 (0.60–1.82) 0.94 (0.53–1.67)
53.5–60.4 14 (33) 15 (31) 17 (18) 35 (23) 0.78 (0.44–1.36) 0.74 (0.41–1.34)
60.4+ 8 (19) 7 (15) 34 (36) 34 (23) 1.02 (0.58–1.79) 1.38 (0.76–2.48)
      (Trend P = 0.83) (Trend P = 0.43)
Body mass index at age 20 (kg/m2)     
<18.5 4 (10) 10 (22) 13 (14) 12 (9) 0.64 (0.35–1.19) 0.77 (0.41–1.45)
18.5–24.9 35 (83) 32 (70) 71 (78) 117 (83) 1.00 1.00
25.0+ 3 (7) 4 (9) 7 (8) 12 (9) 1.02 (0.48–2.15) 1.16 (0.53–2.54)
      (Trend P = 0.23) (Trend P = 0.36)
Body mass index change since age 20 (kg/m2)    
<−1.5 8 (19) 6 (13) 9 (10) 25 (18) 1.59 (0.85–2.97) 1.04 (0.54–2.01)
±1.5 22 (52) 18 (39) 27 (30) 44 (31) 1.00 1.00
>1.5 12 (29) 22 (48) 55 (60) 72 (51) 1.59 (1.02–2.47) 1.34 (0.84–2.14)
      (Trend P = 0.41) (Trend P = 0.26)
Body mass index at diagnosis (kg/m2)    
<18.5 3 (7) 4 (8) 5 (5) 7 (5) 0.74 (0.32–1.72) 1.25 (0.51–3.03)
18.5–24.9 34 (79) 37 (77) 56 (59) 105 (70) 1.00 1.00
25.0+ 6 (14) 7 (15) 34 (36) 38 (25) 1.30 (0.82–2.07) 1.45 (0.89–2.37)
      (Trend P = 0.16) (Trend P = 0.28)
Presence of comorbidity      
None 27 (63) 32 (67) 49 (52) 70 (47) 1.00 1.00
Present 16 (37) 16 (33) 45 (48) 80 (53) 1.69 (1.13–2.52) 0.87 (0.56–1.36)
Smoking       
Never 30 (70) 31 (65) 82 (88) 122 (81) 1.00 1.00
Past 9 (21) 9 (19) 7 (8) 11 (7) 0.40 (0.21–0.75) 0.46 (0.24–0.89)
Current 4 (9) 8 (17) 4 (4) 17 (11) 0.94 (0.48–1.84) 1.94 (0.94–3.99)
      (Trend P = 0.20) (Trend P = 0.53)
Consumption of alcohol      
Never 19 (44) 16 (33) 63 (68) 104 (70) 1.00 1.00
Past 2 (5) 4 (8) 4 (4) 5 (3) 0.45 (0.17–1.15) 0.58 (0.22–1.57)
Current 22 (51) 28 (58) 26 (28) 40 (27) 0.41 (0.26–0.62) 0.60 (0.39–0.94)
      (Trend P < 0.01) (Trend P = 0.02)
Sports club activities at school     
No 16 (38) 21 (44) 52 (55) 90 (60) 1.00 1.00
Present 26 (62) 27 (56) 42 (45) 60 (40) 0.57 (0.38–0.85) 0.83 (0.54–1.26)
Education       
Junior high school 3 (7) 1 (2) 9 (10) 33 (22) 1.00 1.00
High school 19 (44) 30 (64) 59 (63) 78 (52) 1.45 (0.93–2.25) 1.18 (0.75–1.87)
Junior college or higher 21 (49) 16 (34) 26 (28) 38 (26) 4.83 (2.32–10.0) 2.39 (1.08–5.31)
      (Trend P < 0.01) (Trend P = 0.06)
Physical work       
No 40 (95) 43 (93) 86 (91) 135 (91) 1.00 1.00
Present 2 (5) 3 (7) 8 (9) 14 (9) 1.44 (0.68–3.04) 0.85 (0.39–1.85)
Parity       
None 19 (44) 10 (21) 12 (13) 24 (16) 1.00 1.00
Present 24 (56) 38 (79) 82 (87) 125 (84) 2.23 (1.36–3.66) 1.57 (0.93–2.65)
Clinical information      
Involved side       
Hemilateral 18 (42) 17 (35) 37 (39) 69 (46) 1.00 1.00
Bilateral 25 (58) 31 (65) 58 (61) 81 (54) 0.79 (0.53–1.17) 1.14 (0.75–1.75)
Sharp angle       
<45 13 (30) 11 (28) 30 (38) 39 (42) 1.00 1.00
45–48 20 (47) 14 (35) 23 (29) 30 (32) 0.62 (0.36–1.06) 1.04 (0.59–1.84)
49+ 10 (23) 15 (38) 26 (33) 24 (26) 0.72 (0.41–1.25) 1.55 (0.85–2.83)
      (Trend P = 0.22) (Trend P = 0.16)
Acetabular roof obliquity angle     
<20 25 (58) 15 (38) 16 (20) 29 (33) 1.00 1.00
20–26 13 (30) 14 (35) 33 (42) 23 (26) 1.34 (0.78–2.32) 1.11 (0.63–1.95)
27+ 5 (12) 11 (28) 30 (38) 37 (42) 2.61 (1.49–4.57) 2.77 (1.54–5.00)
      (Trend P < 0.01) (Trend P < 0.01)
Acetabular head index (%)     
71.1+ 21 (50) 15 (38) 22 (28) 27 (29) 1.00 1.00
60.0–71.0 13 (31) 14 (35) 26 (33) 34 (37) 1.59 (0.92–2.73) 2.03 (1.15–3.59)
<60.0 8 (19) 11 (28) 31 (39) 31 (34) 1.83 (1.05–3.18) 2.98 (1.64–5.40)
      (Trend P = 0.03) (Trend P < 0.01)
Duration since symptom onset (years)    
<1.0 17 (41) 16 (35) 19 (20) 28 (19) 1.00 1.00
1.0–1.9 13 (32) 8 (17) 23 (24) 31 (21) 1.50 (0.85–2.66) 1.53 (0.85–2.77)
2.0–5.9 5 (12) 13 (28) 36 (38) 41 (28) 1.99 (1.15–3.44) 2.08 (1.18–3.68)
6.0+ 6 (15) 9 (20) 17 (18) 48 (32) 3.16 (1.75–5.70) 3.43 (1.85–6.34)
      (Trend P < 0.01) (Trend P < 0.01)