From: Peri-articular tranexamic acid injection in total knee arthroplasty: a randomized controlled trial
Variable | Group 1: Peri-articular group (n = 30) | Group 2: Intravenous group (n = 30) | P value* |
---|---|---|---|
Blood in Hemovac drain(ml) | |||
24-h postoperative | 300 (+/− 128) | 334 (+/− 124) | 0.279 |
48-h postoperative | 145 (+/− 92) | 186 (+/− 106) | 0.094 |
Total | 445 (+/− 158) | 520 (+/− 175) | 0.081 |
Hematocrit (%) | |||
Preoperative | 36.4 (+/− 3.6) | 37.6 (+/− 3.5) | 0.226 |
24-h postoperative | 29.7 (+/− 3.4) | 30.4 (+/− 4.0) | 0.550 |
48-h postoperative | 31.0 (+/− 2.7) | 31.8 (+/− 3.4) | 0.352 |
Total Hct change (%) (pre op – 48 hr) | −5.4 (+/− 3.1) | −5.8 (+/− 4.4) | 0.730 |
Hemoglobin (g/dL) | |||
preoperative | 12.01 (+/− 1.27) | 12.27 (+/− 1.30) | 0.628 |
24-h postoperative | 9.69 (+/− 1.19) | 10.09 (+/− 1.50) | 0.215 |
48-h postoperative | 10.16 (+/− 0.98) | 10.40 (+/− 1.28) | 0.693 |
Total Hb change (g/dL) (pre op – 48 hr) | −1.85 (+/− 0.95) | −1.87 (+/− 1.37) | 0.840 |
Total blood transfusion (PRC in unit) | 12 | 8 | - |
Number of patients with blood transfusion | 9 | 7 | 0.928 |