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Table 2 Summary Baseline Demographic and Clinical Characteristics of REVITAHIP Participantsa

From: An initial loading-dose vitamin D versus placebo after hip fracture surgery: randomized trial

Variables Active (n = 111) Placebo (n = 107) P value
Sex – n (%)    
 - Female 84 (75.7) 84 (78.5) 0.633
 - Male 27 (24.3) 23 (21.5)
Country of Birth – n (%)    
 - Australia 92 (82.9) 86 (80.4) 0.727
 - Other 19 (17.1) 21 (19.6)
Age    
 Mean (years)b 83.7+/−7.5 84.1+/−7.0 0.726
 Grouped – n (%)    
  - 65-74 yr 15 (13.5) 10 (9.3) 0.772
  - 75-84 yr 43 (38.7) 42 (39.3)
  - 85-94 yr 47 (42.3) 50 (46.7)
  - 95+ yr 6 (5.4) 5 (4.7)
Body mass index (kg/m2)b 24.2+/−3.4 25.1+/−3.8 0.099
Number of days from admission to loading doseb 4.8+/−2.1 5.4+/−2.3 0.049
Pre-injury mobility – n (%)d    
 - Fully independent 80 (72.1) 72 (67.9) 0.156
 - Minimum help 15 (13.5) 15 (14.2)
 - Moderately help 8 (7.2) 7 (6.6)
 - Substantial help 1 (0.9) 8 (7.5)
 - Unable to perform task 7(6.3) 4(3.8)
Pre-injury Modified Barthel index 87.5+/−19.9 86.9+/−22.2 0.852
Pre-injury Functional Comorbidity Index b 3.37+/−2.1 2.9+/−1.7 0.063
Hip Fracture Subtype – n (%)d    
 - Undisplaced subcapital 6 (5.7) 3 (2.8) 0.442
 - Displaced subcapital: 50 (47.2) 48 (45.3)
 - Pertrochanteric simple (2-part) 5 (4.7) 5 (4.7)
 - Pertrochanteric complex (3-part) 27 (25.5) 34 (21.1)
 - Intertrochanteric/basicervical 5 (4.7) 9 (8.5)
 - Subtrochanteric 13 (12.3) 7 (6.6)
Time from fracture to surgery (in hours)b 43.8+/−38.9 38.9+/−25.9 0.272
Hip Fracture Surgeryd    0.655
 - Cannulated screws 4 (3.7) 1 (0.9)
 - Uncemented hemiarthroplasty 15 (14.0) 14 (13.2)
 - Cemented hemiarthroplasty 8 (7.5) 9 (8.5)
 - Total hip replacement 19 (17.8) 20 (18.9)
 - Dynamic hip screw with short plate 14 (13.1) 8 (7.5)
 - Dynamic hip screw with long plate 19 (17.8) 20 (18.9)
 - Gamma nail 28 (26.2) 34 (32.1)
MMSE score (mean, standard deviation)b 26.32+/−4.3 25.7+/−4.4 0.282
Total number of medications usedb 5.1+/−2.6 4.9+/−2.6 0.201
25-hydroxyvitamin D level (nmol/L)c    
 Mean 55.6+/−26.4 49.6+/−19.7 0.112
 Grouped values: n (%)e    
  - <30 13 (16.5) 11 (14.3) 0.621
  - 30-49 22 (27.8) 27 (35.1)  
  - > = 50 44 (55.7) 39 (50.6)  
Grip strength (kgs)b 16.4+/−7.3 15.7+/−6.2 0.478
  1. aPlus-minus values are means +/− SD
  2. bContinuous variables were compared with the use of a two-sample t-test. Categorical variables were compared with the use of a chi-square test
  3. cFor participants given the intervention loading dose after 25-OHD levels were taken (n = 156), (Placebo = 77; Active = 79)
  4. dThe following categories contained missing variables: hip fracture subtype (6 missing, n = 212), hip fracture surgery (6 missing, n = 212), premorbid mobility (1 missing, n = 217)
  5. eNowson CA, McGrath JJ, Ebeling PR, Haikerwal A, Daly RM, Sanders KM, Seibel MJ, Mason RS; Working Group of Australian and New Zealand Bone and Mineral Society, Endocrine Society of Australia and Osteoporosis Australia. Vitamin D and health in adults in Australia and New Zealand: a position statement. Med J Aust. 2012;196(11):686–7 [25]