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Table 2 Factor analysis for repetitive recurrence

From: Clinical outcome of recurrent giant cell tumor of the extremity in the era before molecular target therapy: the Japanese Musculoskeletal Oncology Group study

    Univariate analysis Cox proportional hazards regression analysis
Factors No. of patients (event) 5-y re-recurrent free survival P value Wald Statistic Regression coefficient (B) Relative risk (eB) 95 % CI P value
Age
 < 35 y.o. 66 (18) 0.626 0.332      
 ≥ 35 y.o. 37 (14) 0.594   7.526 1.119 3.062 1.377–6.811 0.006
Gender
 Male 53 (13) 0.656 0.341      
 Female 50 (19) 0.581       
Tumor site
 Upper extremity 79 (23) 0.591 0.089      
 Lower extremity 24 (9) 0.636       
Tumor location
 Site A 95 (29) 0.616 0.557      
 Site B 8 (3) 0.625       
Campanacci
 I 12 (4) 0.550 0.433      
 II 71 (19) 0.657       
 III 20 (9) 0.524       
Initial procedure
 Curettage 98 (30) 0.603 0.785      
En bloc excision 5 (2) 0.800       
Status
 Group P 91 (24) 0.682 0.002      
 Group R 12 (8) 0.563   10.831 1.625 5.078 1.929–13.363 < 0.001
Second surgery
 Curettage 84 (29) 0.541 0.034 8.522 2.054 8.522 1.964–30.590 0.004
En-bloc excision 19 (3) 0.872