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Table 7 Comparison of anthropometric, clinical and densitometric variables between patients with AS taking or not TNF inhibitors

From: Is there a relation between pre-sarcopenia, sarcopenia, cachexia and osteoporosis in patients with ankylosing spondylitis?

  AS patients not taking TNFi N = 45 AS patients taking TNFi N = 22 P
Age (yrs): m (SD) 39.5 (11.4) 43.7 (11.5) NS
Height (m): m (SD) 1.73 (0.06) 1.70 (0.06) NS
Weight (kg): m (SD) 70.6 (14.2) 76.7 (13.3) NS
BMI (kg/m2): m (SD) 23.3 (4.5) 25.7 (4.2) NS
Disease duration (yrs): m (SD) 6.8 (6.0) 14.1 (8.9) 0.0001
FFMI: m (SD) 16.3 (1.8) 16.2 (2.0) NS
FMI: m (SD) 5.9 (3.3) 9.0 (3.5) 0.001
Pre-sarcopenia as defined by Baumgartner : n (%) 23 (51.1) 11 (50.0) NS
Sarcopenia as defined by EWGSOP: n (%) 12 (27.3) 9 (40.9) NS
Cachexia as defined by IWSG : n (%) 7 (15.6) 1 (4.5) NS
LS BMD (g/cm2): m (SD) 1.08 (0.19) 1.19 (0.19) 0.029
LS T-score: m (SD) −0.90 (1.6) −0.07 (1.3) 0.034
TH BMD(g/cm2): m (SD) 0.986 (0.18) 0.945 (0.13) NS
TH T-score: m (SD) −0.50(1.1) −0.70 (1.0) NS
Osteoporosis: n (%) 10 (22.2) 1 (4.5) NS
BASDAI: m (SD) 3.7 (2.3) 3.6 (2.8) NS
BASMI: m (SD) 2.7 (52.5) 3.0 (2.5) NS
BASFI: m (SD) 39.5 (29.8) 41.0 (28.8) NS
Hand grip strength (kg): m (SD) 23.1 (9.2) 23.1 (9.1) NS
Get-up and go test (sec): m (SD) 3.4 (0.5) 2.0 (0.5) NS
Arm circumference (cm): m (SD) 28.0 (3.3) 29.9 (3.8) NS
Waist circumference (cm): m (SD) 88.3 (12.2) 97.5 (10.7) 0.004
MNA test: m (SD) 0.33 (0.4) 0.09 (0.2) 0.015
SASSS: m (SD) 11.6 (18.8) 7.0 (5.2) NS
CRP (mg/l): m (SD) 17.0 (30.2) 11.3 (9.9) NS
ESR (mm/h): m (SD) 29.3 (23.1) 22.3 (15.1) NS
  1. BMI body mass index, BMD: bone mineral density, CRP: C-reactive protein, ESR erythrocyte sedimentation rate, LS lumbar spine, MNA Mini Nutritional Assessment, SASSS Stoke Ankylosing Spondylitis Spinal Score, TH total hip