Table 3 Exposure duration, unadjusted rates and adjusted rate ratios (Cox proportional hazard models) of musculoskeletal hospitalizations in 2002–2006 and 2007–2011
Exposure duration (days) | Hospitalization for musculoskeletal conditions | |||
|---|---|---|---|---|
Total | Median (interquartile range) | Number (unadjusted rate per 100 patient-yrs) | Hazard ratio (95 % CI) | |
2002–2006 | ||||
Anti-TNF | 174 128 | 365.0 (79.0) | 39 (8.18) | 0.95 (0.60, 1.50) |
DMARDs | 358 954 | 365.0 (74.0) | 63 (6.41) | 0.69 (0.46, 1.02) |
Non-user | 184 986 | 349.0 (173.0) | 53 (10.46) | 1.00 (Reference) |
2007–2011 | ||||
Anti-TNF | 213 189 | 365.0 (102.0) | 40 (6.85) | 0.65 (0.37, 1.14) |
DMARDs | 527 820 | 635.0 (54.0) | 70 (4.84) | 0.40 (0.24, 0.66) |
Non-user | 148 381 | 349.5 (181.0) | 35 (8.61) | 1.00 (Reference) |