Table 3 Results of subgroup analyses
SNP | Comparison | Number of datasets | Dominant genetic model | Allele contrast | ||
|---|---|---|---|---|---|---|
OR (95 % CI) | P value | OR (95 % CI) | P value | |||
rs111090870 | Gender | Â | ||||
|  | Female | 7 | 1.13 (1.09–1.16) | <0.001 | 1.21 (1.17–1.25) | 0.000 |
|  | Male | 5 | 1.08 (0.93–1.25) | 0.319 | 1.15 (0.95–1.40) | 0.015 |
|  | Mix gender | 1 | 1.10 (0.99–1.23) | 0.087 | 1.26 (1.09–1.45) | 0.001 |
| Â | Ethnicity | Â | ||||
|  | Asian | 10 | 1.13 (1.09–1.17) | <0.001 | 1.22 (1.16–1.29) | 0.000 |
|  | Caucasian | 3 | 1.09 (1.08–1.22) | <0.001 | 1.17 (1.14–1.21) | 0.000 |
rs678741 | Ethnicity | Â | ||||
|  | Asian | 4 | 0.79 (0.77–0.82) | <0.001 | 0.83 (0.81–0.86) | 0.000 |
|  | Caucasian | 1 | 0.80 (0.74–0.86) | <0.001 | 0.79 (0.73–0.86) | 0.000 |
rs11598564 | Gender | Â | ||||
|  | Female | 3 | 1.14 (1.09–1.16) | <0.001 | 1.20 (1.15–1.25) | 0.000 |
|  | Male | 2 | 1.16 (1.08–1.23) | <0.001 | 1.27 (1.17–1.39) | 0.000 |
rs625039 | Gender | Â | ||||
|  | Female | 3 | 1.07 (1.05–1.09) | <0.001 | 1.13 (1.10–1.17) | 0.000 |
|  | Male | 2 | 1.07 (1.02–1.13) | 0.010 | 1.20 (1.12–1.29) | 0.000 |
|  | Mix gender | 1 | 1.05 (0.96–1.14) | 0.256 | 1.14 (1.02–1.28) | 0.025 |