Skip to main content

Table 2 Summary of different genetic model comparison results

From: Associations of LBX1 gene and adolescent idiopathic scoliosis susceptibility: a meta-analysis based on 34,626 subjects

SNP Genetic model OR (95 % CI) Z P value I2% P het Effect model Egger’s test
t value P value
rs111090870 TT + TC vs. CC 1.12 (1.09–1.15) 7.66 0.000 68.8 <0.001 R 0.42 0.684
TT vs. TC + CC 1.42 (1.36–1.49) 15.49 0.000 42.6 0.058 F 0.92 0.378
TT vs. CC 1.36 (1.27–1.45) 9.07 0.000 73.2 <0.001 R 0.98 0.349
TC vs. CC 1.13 (1.09–1.18) 5.92 0.000 56.3 0.009 R −0.07 0.949
T vs. C 1.21 (1.16–1.26) 9.52 0.000 68.7 <0.001 R 0.55 0.597
rs678741 GG + GA vs. AA 0.79 (0.77–9.82) 16.79 0.000 0.0 0.998 F 0.85 0.458
GG vs. GA + AA 0.69 (0.64–0.74) 10.98 0.000 0.0 0.880 F −0.82 0.470
GG vs. AA 0.68 (0.65–0.72) 13.22 0.000 0.0 0.517 F −1.09 0.356
GA vs. AA 0.88 (0.85–0.91) 8.12 0.000 0.0 0.904 F −0.73 0.519
G vs. A 0.83 (0.81–0.85) 13.75 0.000 0.0 0.743 F −0.69 0.542
rs11598564 GG + GA vs. AA 1.13 (1.10–1.16) 7.98 0.000 0.0 0.649 F 0.32 0.769
GG vs. GA + AA 1.09 (0.84–1.43) 0.64 0.519 88.8 <0.001 R 0.29 0.726
GG vs. AA 1.12 (1.33–1.52) 10.12 0.000 0.0 0.761 F −0.71 0.526
GA vs. AA 1.13 (1.08–1.18) 5.34 0.000 0.0 0.739 F 1.02 0.384
G vs. A 1.21 (1.16–1.25) 10.03 0.000 22.2 0.273 F 0.66 0.557
rs625039 GG + GA vs. AA 1.07 (1.05–1.09) 7.45 0.000 0.0 0.648 F 0.20 0.850
GG vs. GA + AA 1.30 (1.23–1.37) 9.05 0.000 0.0 0.509 F 1.18 0.303
GG vs. AA 1.17 (1.13–1.21) 9.48 0.000 0.0 0.651 F 0.66 0.545
GA vs. AA 1.09 (1.05–1.12) 4.66 0.000 0.0 0.573 F −0.35 0.747
G vs. A 1.14 (1.11–1.17) 10.14 0.000 0.0 0.584 F 1.10 0.333
  1. SNP single nucleotide polymorphism; OR odds ratio; CI confidence interval; F fix-effect model; R random-effect model; P het P value for heterogeneity
  2. P < 0.05 stands for statistical significance