Fig. 3From: Safety and pharmacodynamic dose response of short-term prednisone in healthy adult subjects: a dose ranging, randomized, placebo-controlled, crossover studyMean change from baseline (difference from placebo) in biomarkers of bone metabolism. Change in osteocalcin (OC), procollagen type 1 N-propeptide (P1NP), and urinary N-terminal cross-linked telopeptide of type 1 collagen (uNTX) for each daily dose of prednisone. a OC: Day 1 by hour; (b) OC: Days 1–8; (c) P1NP: Days 1–8; (d) uNTX: Days 1–8. *P ≤ 0.05 and **P ≤ 0.01 versus placeboBack to article page