Treatment of critically sized femoral defects with recombinant BMP-2 delivered by a modified mPEG-PLGA biodegradable thermosensitive hydrogel

Table 3 Radiographic assessment of bone defect healing in rabbits

Groups	Number of animals with radiographic healing
Groups	8 weeks	12 weeks
Untreated	0/6	0/6
Autograft	6/6	6/6
BOX hydrogel	0/6	0/6
BOX hydrogel + 5 μg/ml BMP-2	1/6	2/6
BOX hydrogel + 10 μg/ml BMP-2	3/6	4/6
BOX hydrogel + 20 μg/ml BMP-2	6/6	6/6

ISSN: 1471-2474