Fig. 5

In vitro cytotoxicity of mPEG-PLGA and BOX hydrogel copolymers. The leachates of mPEG-PLGA or BOX hydrogels (5–30 wt%) were prepared as described in Materials and Methods. L929 cells (a) and hFOB1.19 cells (b) were cultured for 1 or 3 days in the 1:1 mixed medium of culture media and copolymer leachates. Cell proliferation was measured by XTT assay. *P < 0.05, the statistical comparisons for BOX-hydrogel treatment versus mPEG-PLGA-hydrogel treatment