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Table 4 An overview and key findings of the four studies included in the review

From: Multidisciplinary approaches to managing osteoarthritis in multiple joint sites: a systematic review

Studies & trial design Sample size Setting Health disciplines OA sites Mean age of participants (SD) Primary outcomes within studies Secondary outcomes within studies Key findings of studies
Hopman-Rock & Westhoff (2000) [16]
N = 105
Intervention = 56
Control = 49
Single Centre
Primary Care
Physiotherapy, Occupational Therapy (OT) and General Practitioner Hip or Knee Intervention
=65.4 (5.3)
=65.2 (5.7)
IRGL self-reported pain. Pain severity (VAS) QoL (VAS)
QoL seven question sum score
Activity restriction, ROM
Muscle strength
Observed activity restrictions
Healthcare utilisation, lifestyle behaviour, BMI
Significant MANOVA effects were found for pain, QoL, quadriceps, BMI, physically active lifestyle, and visits to the physical therapist. Most effects were moderate at post-test assessment and smaller at follow-up. No effects were found for range of ROM or functional tasks
van Baar et al. (2001) [19]
Single blind RCT
N = 201
Intervention = 99
Control = 102
Multi-Centre (Netherlands)
Primary Care
General Practitioner and Physiotherapy Hip or Knee Intervention
68.3 (8.4)
=67.7 (9.2)
IRGL self-reported disability, VAS pain in the past week Observed disability, Drug use NSAIDs/paracetamol, Global perceived effect, muscle strength & ROM hip, knee, physical activity At 24 weeks exercise treatment was associated with a small to moderate effect on pain during the past week (difference in change between the two groups −11.5 (95 % CI −19.7 to −3.3). At 36 weeks no differences were found between groups.
Rosemann et al. (2007) [18]
3-arm pragmatic cluster trial
N = 1021
Intervention 1
Intervention 2
Control = 332
Multi-Centre (Germany)
Primary Care
General Practitioner and Practice nurse Hip or Knee Intervention 1 = 65.59 (14.68)
Intervention 2 = 66.27 (15.19)
=66.11 (15.02)
AIMS2-SF QoL, lower body, upper body, symptom & social. IPAQ physical activity, BMI, prescriptions. Health service utilisation Compared with the control group, for intervention group II, significant changes in the AIMS2-SF dimensions social (p < 0.001), symptom (p = 0.048), and lower body (p = 0.049) were identified. Radiographs (P = 0.031) and orthopaedic referrals (p = 0.044) decreased whereas prescriptions of pain relievers increased significantly.
Hansson et al. (2010) [17]
Single blind RCT
N = 114
Intervention = 61 Control = 53
Single Centre (Sweden)
Primary Care
Physiotherapy, OT, Orthopaedic Specialist, Nurse, Nutritionist Knee, Hip or Hand Intervention
=62 (9.43)
=63 (9.51)
EQ5D index and EQ5D VAS ASES pain, function & other symptoms. GAT, SOLEO, SOLEC, One legged jump/raising, OA location & BMI Significant differences between the intervention group and the control group, comparing the results at baseline and after 6 months in EuroQol-5D (p < 0.001) and in SOLEC (p = 0.02) in favour of the intervention group.
  1. Key: AIMS2 Arthritis Impact Measurement Scale, ASES Arthritis Self-Efficacy Scale, BMI Body Mass Index, EQ-5D Euro QoL, European Quality of Life measure, GAT Grip Ability Test, IPAQ International Physical Activity Questionnaire, GP General Practitioner, IRGL Impact of Rheumatic Disease on General Health and Lifestyle, NSAIDs Non-steroidal anti-inflammatory drugs, QoL Quality of Life, ROM Range of Movement, VAS Visual Analogue Scale, SOLEO Stand On One Leg Eyes Open, SOLEC Stand On One Leg Eyes Closed