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Table 1 Comparison of psychophysical responses among knee OA patients (n = 35) and pain-free controls (n = 39)

From: Variability in conditioned pain modulation predicts response to NSAID treatment in patients with knee osteoarthritis

 

Knee OA (n = 35)

Controls (n = 39)

Variables of Interest Assessed During the QST Session

Current Clinical Pain (0–100)

34.3 ± 26.2**

0 ± 0

Anxiety during QST (0–100)

23.1 ± 20.7 **

5.5 ± 7.1

Mechanical and Cold Pressor Responses

PPTh (KPa)- Trapezius

275.1 ± 142.3*

346.4 ± 130.0

PPTh (KPa)- Thumb

227.5 ± 91.0**

339.9 ± 94.6

PPTh (KPa)- Knee

315.9 ± 158.0**

510.2 ± 188.6

Cuff Pain Threshold (mmHg)

129.3 ± 51.4*

168.6 ± 76.1

Cold Pain Tolerance (sec)

29.7 ± 30.8**

72.3 ± 60.5

Maximum Cold Pain (0–100)

75.9 ± 21.7

73.8 ± 22.2

CPM Index

118.7 ± 36.8*

142.5 ± 28.6

Other Mechanical and Cold Pressor Data Appear in Figs. 1 and 2

  1. QST quantitative sensory testing, PPTh pressure pain threshold, KPa Kilopascales, CPM conditioned pain modulation
  2. *p < 0.05 for the group comparison
  3. **p < 0.01 for the group comparison