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Table 1 Summary of demographics and baseline characteristics

From: Treatment patterns and costs for anti-TNFα biologic therapy in patients with psoriatic arthritis

 

Patients With Only First-line Biologic Therapy (n = 881)a

Patients With Second-line Biologic Therapy (n = 72)b

Patients With Third-line or Greater Biologic Therapy (n = 37)a,b

Overall (N = 990)

Age (y), mean (SD)

49.1 (11.0)

48 (10.9)

48.8 (9.5)

49.0 (10.9)

Female, n (%)

387 (43.9)

42 (58.3)

22 (59.5)

451 (45.6)

US region, n (%)

    

 Northeast

127 (14.4)

11 (15.3)

4 (10.8)

142 (14.3)

 North central

209 (23.7)

11 (15.3)

8 (21.6)

228 (23.0)

 South

357 (40.5)

32 (44.4)

15 (40.5)

404 (40.8)

 West

182 (20.7)

18 (25.0)

10 (27.0)

210 (21.2)

 Unknown

6 (0.7)

0

0

6.0 (0.6)

Health insurance, n (%)

 FFS

721 (81.8)

54 (75.0)

32 (86.5)

807 (81.5)

 HMO and POS capitation

137 (15.6)

18 (25.0)

5 (13.5)

160 (16.2)

 Missing/unknown

23 (2.6)

0

0

23 (2.3)

Index biologic therapies, n (%)

 Etanercept

389 (44.2)

31 (43.1)

15 (40.5)

435 (43.9)

 Adalimumab

391 (44.4)

32 (44.4)

14 (37.8)

437 (44.1)

 Infliximab

67 (7.6)

3 (4.2)

7 (18.9)

77 (7.8)

 Golimumab

34 (3.9)

6 (8.3)

1 (2.7)

41 (4.1)

Comorbidities, n (%)c

 Type 2 diabetes

203 (23.0)

11 (15.3)

10 (27.0)

224 (22.6)

 Hypertension

400 (45.4)

33 (45.8)

18 (48.6)

451 (45.6)

 Hyperlipidemia

337 (38.3)

23 (31.9)

15 (40.5)

375 (37.9)

 Ischemic heart disease

75 (8.5)

4 (5.6)

4 (10.8)

83 (8.4)

 Any of the above

563 (63.9)

41 (56.9)

25 (67.6)

629 (63.5)

  1. PsA, psoriatic arthritis; FFS, fee-for-service; HMO, health maintenance organization; POS, point-of-service; SD, standard deviation; TNFα, tumor necrosis factor-α
  2. aBiologic therapy refers to the following anti-TNFα agents: etanercept, adalimumab, infliximab, and golimumab. bAmong this group of patients, 18 (43 %) switched to a fourth-line of biologic treatment. cIdentification was based on non–rule-out diagnoses