Table 2 Analysis of IL17 genotypes in relation to age of disease diagnosis, presence of rheumatoid factor, erosive disease and extra-articular manifestations in RA patients
From: IL17A and IL17F gene polymorphisms in patients with rheumatoid arthritis
Genotype | Age of disease diagnosis | Rheumatoid Factor positive | Erosive RA | Extra-articular manifestations | |||||
|---|---|---|---|---|---|---|---|---|---|
Mean [years] | SD | p a | (%) | p b | (%) | p b | (%) | p b | |
IL17A rs2275913 | |||||||||
 GG | 46.6 | 13.3 | 0.56 | 72.02 | 0.35 | 80.23 | 0.64 | 14.45 | 0.25 |
 AG | 48.1 | 13.2 | 78.61 | 81.87 | 19.69 | ||||
 AA | 46.6 | 12.8 | 74.00 | 76.00 | 11.76 | ||||
IL17F rs763780 | |||||||||
 TT | 47.3 | 13.2 | 0.69 | 75.60 | 0.70 | 80.16 | 0.52 | 16.10 | 0.14 |
 CT | 49.0 | 12.2 | 74.29 | 82.86 | 28.57 | ||||
 CC | 44.5 | 33.2 | 50.00 | 50.00 | 0.00 | ||||
IL17F rs11465553 | |||||||||
 CC | 47.5 | 13.4 | 0.63 | 75.27 | 1.00 | 79.84 | 0.69 | 18.21 | 0.084 |
 CT | 46.7 | 12.0 | 76.19 | 83.72 | 6.98 | ||||
IL17F rs2397084 | |||||||||
 TT | 47.6 | 13.1 | 0.69 | 75.08 | 0.04* | 80.06 | 0.78 | 16.62 | 0.69 |
 CT | 46.4 | 14.0 | 78.48 | 80.49 | 19.28 | ||||
 CC | 50.5 | 6.4 | 0.00 | 100.00 | 0.00 | ||||