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Table 7 Discrete choice model of association between GI events and receipt of bisphosphonate treatment (versus non-bisphosphonate)a

From: Association between gastrointestinal events and osteoporosis treatment initiation in women diagnosed with osteoporosis in France: a retrospective analysis

Effect

Estimated odds ratio

95 % CI

p value

Pre-index GI event (ref: no pre-index GI event)

0.846

(0.74, 0.95)

0.0009

Post-index GI event (ref: no post-index GI event)

0.654

(0.57, 0.74)

<0.0001

Age group

   

 65–74 vs. 55–64

0.962

(0.87, 1.06)

0.0613

 75–84 vs. 55–64

0.785

(0.71, 0.87)

0.0023

 85+ vs. 55–64

0.720

(0.54, 0.97)

0.0624

Pre-index Medication Use

   

 Gastro-protective agents

0.684

(0.62, 0.76)

<0.0001

 NSAIDs

1.066

(0.97, 1.17)

0.1835

 Glucocorticoids

0.982

(0.88, 1.09)

0.7334

Charlson comorbidity index score

0.961

(0.92, 1.01)

0.0963

  1. NSAIDs non-steroidal anti-inflammatory drugs
  2. aAmong patients who initiated treatment
  3. CI confidence interval