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Table 5 Logistic regression analysis of association between GI events and type of osteoporosis treatment initiated

From: Association between gastrointestinal events and osteoporosis treatment initiation in women diagnosed with osteoporosis in France: a retrospective analysis

Effect Initiated bisphosphonates vs. initiated non-bisphosphonates
Post-index GI event (ref: no post-index GI event) Odds ratio 95 % CI p value
 Among patients without pre-index GI problems 0.591 (0.55, 0.64) <0.0001
 Among patients with pre-index GI problems 0.631 (0.58, 0.68) <0.0001
Age group    
 65–74 vs. 55–64 1.393 (1.00, 1.95) 0.0603
 75–84 vs. 55–64 1.576 (1.18, 2.01) <0.0001
 85+ vs. 55–64 1.154 (0.77, 1.75) 0.2332
Pre-index medication use    
 Gastro-protective agents 1.693 (1.21, 2.38) <0.0001
 NSAIDs 1.094 (0.86, 1.39) 0.3443
 Glucocorticoids 1.066 (0.78, 1.46) 0.4532
Charlson comorbidity index score 1.004 (0.88, 1.15) 0.3594
  1. CI confidence interval