Skip to main content

Table 2 Crude and adjusted OR (95 % CI) for radiographic OA between participants with and without gout

From: The association between gout and radiographic hand, knee and foot osteoarthritis: a cross-sectional study

Radiographic OA definition

Gout

No gout

Crude OR (95 % CI)

Adjusted OR (95 % CI)

Hand

n = 53

n = 211

 

a

Radiographic OA (K&L ≥ 2) affecting IPJs on at least two rays on each hand (%)

10 (19)

28 (13)

1.57 (0.69, 3.60)

1.46 (0.61, 3.50)

Moderate to severe radiographic OA (K&L ≥ 3) affecting IPJs on at least two rays on each hand (%)

3 (6)

12 (6)

1.00 (0.24, 4.11)

1.02 (0.22, 4.70)

Total number of joints affected by radiographic OA in the hand (K&L ≥ 2) [0–32]:

 0 (%)

17 (32)

62 (29)

1.00

1.00

 1–2 (%)

15 (28)

62 (29)

0.91 (0.41, 2.03)

0.85 (0.37, 1.97)

 3–7 (%)

13 (25)

65 (31)

0.72 (0.30, 1.75)

0.65 (0.26, 1.67)

  ≥ 8 (%)

8 (15)

22 (10)

1.39 (0.46, 4.15)

1.24 (0.38, 4.06)

Total number of joints affected by moderate to severe radiographic OA in the hand (K&L ≥ 3) [0–32]:

 0 (%)

34 (64)

134 (64)

1.00

1.00

 1–2 (%)

8 (15)

46 (22)

0.76 (0.33, 1.77)

0.69 (0.29, 1.63)

 3–7 (%)

7 (13)

25 (12)

1.17 (0.46, 2.98)

1.16 (0.45, 3.00)

  ≥ 8 (%)

4 (8)

6 (3)

3.48 (0.69, 17.72)

3.57 (0.62, 20.45)

Knee

n = 27

n = 108

 

b

Radiographic OA (K&L ≥ 2 or Burnett grade ≥ 1) affecting the TF joint in either knee (%)

11 (41)

49 (45)

0.82 (0.33, 1.99)

0.44 (0.15, 1.29)

Radiographic OA (K&L ≥ 2 or Burnett grade ≥ 1) affecting the PF joint in either knee (%)

20 (74)

76 (70)

1.22 (0.45, 3.29)

0.70 (0.22, 2.22)

Radiographic OA (K&L ≥ 2 or Burnett grade ≥ 1) affecting the TF and PF joints in either knee (%)

11 (41)

41 (38)

1.13 (0.46, 2.78)

0.57 (0.20, 1.65)

Radiographic OA (K&L ≥ 3 or Burnett grade 3) affecting the TF joint in either knee (%)

4 (15)

27 (25)

0.51 (0.16, 1.63)

0.28 (0.07, 1.09)

Radiographic OA (K&L ≥ 3 or Burnett grade 3) affecting the PF joint in either knee (%)

7 (26)

26 (24)

1.13 (0.39, 3.25)

0.58 (0.18, 1.86)

Radiographic OA (K&L ≥ 3 or Burnett grade 3) affecting the TF and PF joints in either knee (%)

3 (11)

10 (9)

1.22 (0.32, 4.71)

0.54 (0.12, 2.40)

Foot

n = 25

n = 99

 

c

Radiographic OA (Menz ≥ 2) affecting at least one of 1st MTPJ, 1st CMJ, 2nd CMJ, N1stCJ and TNJ in either foot (%)

20 (80)

67 (68)

2.22 (0.69, 7.15)

2.16 (0.66, 7.06)

Severe radiographic OA (Menz ≥ 3) affecting at least one of 1st MTPJ, 1st CMJ, 2nd CMJ, N1stCJ and TNJ in either foot (%)

7 (28)

21 (21)

1.46 (0.54, 3.94)

1.45 (0.53, 3.97)

Total number of joints affected by radiographic OA (Menz ≥ 2) [0–10]:

 0 (%)

5 (20)

32 (32)

1.00

1.00

 1–2 (%)

10 (40)

46 (46)

1.64 (0.47, 5.72)

1.55 (0.44, 5.47)

  ≥ 3 (%)

10 (40)

21 (21)

3.86 (0.97, 15.31)

4.00 (0.99, 16.10)

Total number of joints affected by severe radiographic OA (Menz ≥ 3) [0–10]:

 0 (%)

18 (72)

78 (79)

1.00

1.00

 1–2 (%)

7 (28)

21 (21)

1.46 (0.54, 3.94)

1.45 (0.53, 3.97)

Radiographic OA (Menz ≥ 2) affecting either 1st MTPJ (%)

13 (52)

37 (37)

1.90 (0.75, 4.78)

1.85 (0.73, 4.69)

Radiographic OA (Menz ≥ 2) affecting either 1st CMJ (%)

2 (8)

13 (13)

0.59 (0.13, 2.75)

0.54 (0.11, 2.56)

Radiographic OA (Menz ≥ 2) affecting either 2nd CMJ (%)

7 (28)

24 (24)

1.26 (0.45, 3.54)

1.34 (0.46, 3.91)

Radiographic OA (Menz ≥ 2) affecting either N1stCJ (%)

6 (24)

12 (12)

2.46 (0.78, 7.73)

2.60 (0.80, 8.46)

Radiographic OA (Menz ≥ 2) affecting either TNJ (%)

10 (40)

23 (23)

2.18 (0.87, 5.46)

2.24 (0.88, 5.70)

  1. aAdjusted for BMI, diuretic use and hand pain. bAdjusted for BMI, diuretic use and knee pain. c Adjusted for BMI and diuretic use. K&L Kellgren and Lawrence, IPJs interphalangeal joints, OR odds ratio, CI confidence interval, TF tibiofemoral, PF patellofemoral, 1st MTPJ first metatarsophalangeal joint, CMJ cuneometatarsal joint, N1stCJ navicular first cuneiform joint, TNJ talonavicular