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Table 3 Multiple regression model of unstandardized (b) coefficients for primary and secondary outcomes, measured 1-year follow-up, by depression/anxiety severity at baseline

From: Are depression and anxiety associated with disease activity in rheumatoid arthritis? A prospective study

  Primary outcome    Secondary outcomes
  DAS28 ESR SJC TJC PGA
  b(SE) 95 % CI p b(SE) 95 % CI p b(SE) 95 % CI p b(SE) 95 % CI p b(SE) 95 % CI p
Unadjusted                
Depression 0.06 (0.02) 0.10,0.45 0.01 0.01 (0.04) −0.06,0.09 0.74 0.12 (0.13) −0.14,0.38 0.35 0.55 (0.22) 0.11,0.99 0.02 2.68 (0.80) 1.07,4.28 <0.01
Anxiety 0.04 (0.02) −0.00,0.07 0.05 0.02 (0.03) −0.05,0.08 0.63 0.06 (0.11) −0.16,0.29 0.57 0.34 (0.20) −0.06,0.75 0.09 2.30 (0.72) 0.85,3.75 <0.01
Adjusted a                
Depression 0.03 (0.02) −0.00,0.06 0.07 0.01 (0.02) −0.03,0.05 0.69 0.19 (0.13) −0.07,0.45 0.16 0.59 (0.23) 0.13,1.05 0.01 2.07 (0.80) 0.46,3.69 0.01
Anxiety 0.02 (0.01) −0.00,0.05 0.06 0.02 (0.02) −0.02,0.05 0.37 0.15 (0.11) −0.07,0.38 0.18 0.44 (0.20) 0.04,0.85 0.03 2.13 (0.65) 0.81,3.45 <0.01
  1. DAS28 28-joint disease activity score, ESR erythrocyte sedimentation rate, SJC swollen joint count, TJC tender joint count, PGA patient global assessment
  2. aModel adjusted for age, disease duration and baseline physical health for each variable (e.g. DAS28 at baseline adjusted for in DAS28 outcome assessment; ESR at baseline adjusted for in ESR outcome assessment; etc.)
  3. Bold text denotes significant association