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Table 3 Multiple regression model of unstandardized (b) coefficients for primary and secondary outcomes, measured 1-year follow-up, by depression/anxiety severity at baseline

From: Are depression and anxiety associated with disease activity in rheumatoid arthritis? A prospective study

 

Primary outcome

  

Secondary outcomes

 

DAS28

ESR

SJC

TJC

PGA

 

b(SE)

95 % CI

p

b(SE)

95 % CI

p

b(SE)

95 % CI

p

b(SE)

95 % CI

p

b(SE)

95 % CI

p

Unadjusted

               

Depression

0.06 (0.02)

0.10,0.45

0.01

0.01 (0.04)

−0.06,0.09

0.74

0.12 (0.13)

−0.14,0.38

0.35

0.55 (0.22)

0.11,0.99

0.02

2.68 (0.80)

1.07,4.28

<0.01

Anxiety

0.04 (0.02)

−0.00,0.07

0.05

0.02 (0.03)

−0.05,0.08

0.63

0.06 (0.11)

−0.16,0.29

0.57

0.34 (0.20)

−0.06,0.75

0.09

2.30 (0.72)

0.85,3.75

<0.01

Adjusted a

               

Depression

0.03 (0.02)

−0.00,0.06

0.07

0.01 (0.02)

−0.03,0.05

0.69

0.19 (0.13)

−0.07,0.45

0.16

0.59 (0.23)

0.13,1.05

0.01

2.07 (0.80)

0.46,3.69

0.01

Anxiety

0.02 (0.01)

−0.00,0.05

0.06

0.02 (0.02)

−0.02,0.05

0.37

0.15 (0.11)

−0.07,0.38

0.18

0.44 (0.20)

0.04,0.85

0.03

2.13 (0.65)

0.81,3.45

<0.01

  1. DAS28 28-joint disease activity score, ESR erythrocyte sedimentation rate, SJC swollen joint count, TJC tender joint count, PGA patient global assessment
  2. aModel adjusted for age, disease duration and baseline physical health for each variable (e.g. DAS28 at baseline adjusted for in DAS28 outcome assessment; ESR at baseline adjusted for in ESR outcome assessment; etc.)
  3. Bold text denotes significant association