The efficacy of continuous-flow cryo and cyclic compression therapy after hip fracture surgery on postoperative pain: design of a prospective, open-label, parallel, multicenter, randomized controlled, clinical trial

Table 2 Hospital protocols

		Analgesic protocol
Hospital	Thrombosis prophylaxis	Standard		As needed
Spaarne Gasthuis, Hoofddorp	Fraxiparine 2850 IU 1x^a	Acetaminophen 1000 mg 4x	Diclofenac 50 mg 3x^b	PCA-iv morphine	or	Morphine 10 mg 6x sc^cor Oramorph 10 mg 6x^c
Spaarne Gasthuis, Hoofddorp	Fraxiparine 2850 IU 1x^a	Acetaminophen 1000 mg 4x	Diclofenac 50 mg 3x^b	If considered able	or	Morphine 10 mg 6x sc^cor Oramorph 10 mg 6x^c
Noordwest Ziekenhuisgroep	Fraxiparine 2850 IU 1x^a	Acetaminophen 1000 mg 4x	Diclofenac 50 mg 3x^b	PCA-iv morphine	or	Morphine 10 mg 6x sc^cor Oxycodone 10 mg 6x^c
Noordwest Ziekenhuisgroep	Fraxiparine 2850 IU 1x^a	Acetaminophen 1000 mg 4x	Diclofenac 50 mg 3x^b	If considered able	or	Morphine 10 mg 6x sc^cor Oxycodone 10 mg 6x^c
VU University medical center	Fraxiparine 2850 IU 1x^a	Acetaminophen 1000 mg 4x	Diclofenac 50 mg 3x^b	Morphine 10 mg 6x sc^c	or	Oxycodone 10 mg 6x^c
Spaarne Gasthuis, Haarlem	Fraxiparine 2850 IU 1x^a	Acetaminophen 1000 mg 4x	Diclofenac 50 mg 3x or 75 mg iv 2x^b	Morphine 10 mg 6x sc^c	or	Oxycodone 10 mg 6x^c
Amstelland Hospital	Enoxaparine 40 mg 1x	Acetaminophen 1000 mg 3x	Diclofenac 75 mg im/iv 2x^b	PCA-iv morphine	or	Piritramide 10 mg 6x sc^cor Tramadol 50 mg 3x
Amstelland Hospital	Enoxaparine 40 mg 1x	Acetaminophen 1000 mg 3x	Diclofenac 75 mg im/iv 2x^b	If considered able	or	Piritramide 10 mg 6x sc^cor Tramadol 50 mg 3x

Reported dosages are dosages given in 24 h
im intramuscular, iv intravenous, sc subcutaneous, PCA patient controlled analgesia
^aDosage is doubled in patients weighing > 80 kg
^bIf no contraindications exist. ^c: Dosage is reduced by 50 % in patients aged ≥ 70 years

ISSN: 1471-2474