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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: The protective role of autophagy in experimental osteoarthritis, and the therapeutic effects of Torin 1 on osteoarthritis by activating autophagy

Fig. 1

The mRNA expression of VEGF, MMP-13 and TIMP-1. a, b The mRNA expression levels of VEGF and MMP-13 in IL-1β-induced SW1353 cells were significantly increased compared with that in normal cells. c The mRNA expression level of TIMP-1 was significantly decreased. The increase in VEGF and MMP-13 expression, and decrease in TIMP-1 expression were significantly inhibited by Torin 1, while the effects of 3-MA were exactly opposite. n = 3 for each group, and the test was repeated 3 times. *P < 0.05, **P < 0.01, ***P < 0.001

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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