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Table 1 Inclusion and exclusion criteria

From: Focal cartilage defects in the knee –a randomized controlled trial comparing autologous chondrocyte implantation with arthroscopic debridement

Inclusion criteria Exclusion criteria
-Age 18–50 years old -Osteoarthritis, rheumatoid or other systemic arthritis
-Single symptomatic cartilage defect on medial or lateral femoral condyle or trochlea -Malalignment >5° measured on HKA images
-Defect size larger than 2 cm2 -No radiological osteoarthritis
-Lesion graded ICRS 3–4 -Obesity (Body mass index > 30)
- > 50 % intact meniscus -Comorbidities that may influence surgery or rehabilitation
-Ligamentous stable knee -Pregnancy
-Acceptable range of motion (5–105°) -Inability to complete questionnaires or rehabilitation
-Lysholm score < 75 -Serious alcohol or drug abuse
-Informed consent -Previous surgery to the chondral defect except OCD surgery