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Table 2 Levels of endocannabinoids, linoleic acid-related oxylipins and related lipids in blood samples from controls and subjects with CWP or NP

From: Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain

  

Morning sampling

Afternoon sampling

 

Lipid

Condition

Median

iqr

Median

iqr

P value

2-AG

Control

5382

4342

6386

11471

C: 0.35

 

NP

4325

4139

4820

3483

T: 0.047

 

CWP

3279

2865

8303

14621

C x T: 0.17

AEA

Control

179

63

189

140

C: 0.14

 

NP

260

195

217

121

T: 0.50

 

CWP

156

215

221

227

C x T: 0.21

PEA

Control

1930

714

2728

1197

C: 0.35

 

NP

3153

1531

2726

1263

T: 0.19

 

CWP

2084

1510

2961

2266

C x T: 0.074

SEA

Control

8439

5048

11220

5427

C: 0.97

 

NP

9060

5435

9982

5219

T: 0.072

 

CWP

11310

11256

10690

7528

C x T: 0.56

OEA

Control

926

1685

1767

988

C: 0.20

 

NP

1861

1145

1761

1009

T: 0.81

 

CWP

1760

1364

1291

1875

C x T: 0.080

LEA

Control

619

184

950

455

C: 0.39

 

NP

961

425

780

431

T: 0.32

 

CWP

619

806

710

1220

C x T: 0.024

9-HODE

Control

13247

31114

26587

20201

C: 0.75

 

NP

23724

11755

13251

16879

T: 0.73

 

CWP

23943

36239

17527

29853

C x T: 0.11

13-HODE

Control

35679

43458

43935

37629

C: 0.22

 

NP

39311

13634

20330

17000

T: 0.49

 

CWP

24137

44109

17188

36591

C x T: 0.12

9,10-DiHOME

Control

4498

12601

7585

12910

C: 0.49

 

NP

6494

8772

4056

4132

T: 0.39

 

CWP

3294

13986

2054

4791

C x T: 0.32

12,13-DiHOME

Control

15725

15768

15935

14365

C: 0.24

 

NP

13637

7522

10021

11471

T: 0.57

 

CWP

9716

14338

5342

12263

C x T: 0.70

9,10,13-TriHOME

Control

214

189

284

144

C: 0.63

 

NP

201

239

289

209

T: 0.36

 

CWP

210

171

221

163

C x T: 0.85

9,12,13-TriHOME

Control

2131

3191

3731

4845

C: 0.98

 

NP

1657

4282

4173

6797

T: 0.41

 

CWP

3007

2834

2761

5927

C x T: 0.51

13-oxo-ODE

Control

1485

1002

1477

1799

C: 0.51

 

NP

1781

1513

1146

1498

T: 0.64

 

CWP

1188

2179

1280

1423

C x T: 0.049

5-HETE

Control

718

437

1065

761

C: 0.93

 

NP

907

692

766

538

T: 0.28

 

CWP

745

770

852

822

C x T: 0.10

8,9-DiHETrE

Control

145

55

146

45

C: 0.39

 

NP

180

74

156

56

T: 0.18

 

CWP

164

171

125

123

C x T: 0.77

  1. Data are given as medians and the interquartile ranges (iqr) for the concentrations in pM. The sample sizes for the samples taken during the morning and afternoon, respectively, were: control, 15 and 12; NP, 17 and 17; CWP 5 and 9. P values from two-way robust Wilcoxon analyses [22, 23] show main effects of condition (“C”), sampling time (“T”) and the interaction C × T. P values <0.05 are shown in bold text
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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