Fig. 2

Expression of miR-140-3p (a), miR-140-5p (b), miR-181a-5p (c), miR-181d-5p (d), and miR-451a (e) in standard healing fractures (solid bars) and in unhealing fractures (blank bars) on post-fracture days 3 and 7, as analyzed by real-time PCR. All graphs show the fold change in expression when expression in the standard healing fracture on day 3 was normalized as 1. Values are the mean ± standard error (n = 5 in each group at each time point). *p < 0.05 for indicated groups. a, p < 0.05 versus values on day 3 in standard healing fracture; b, p < 0.05 versus values on day 7 in standard healing fracture; c, p < 0.05 versus values on day 10 in standard healing fracture; d, p < 0.05 versus values on day 21 in standard healing fracture; e, p < 0.05 versus values on day 28 in standard healing fracture