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Table 1 The characteristics of included studies

From: The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis

Study (year) Study type No. IA vs IV Age: IA vs IV TXA group Transfusion criteria Thromboprophylaxis Level of evidence
Alshryda 2013 [22] RCT 80/81 66/63 1 g Hb <70 g/l LMWH A
BagsBy 2014 [24] nRCT 91/90 61.4/61.9 1 g Hb <70 g/l Warfarin/Asprin B
Chang 2014 [14] nRCT 154/234 57.2/56.7 3 g Hb <100 g/l -- B
Ding 2014 [23] nRCT 30/30 60/61 3 g Hb <80 g/l -- B
Fan 2014 [15] RCT 55/44 66.0/66.5 2 g Hb <70 g/l Physical A
Gilbody 2014 [16] nRCT 86/88 64/65 3 g Hb <80 g/l enoxaparin B
Konig G 2013 [17] nRCT 91/40 60/59 3 g Hb <80 g/l -- B
Machin 2014 [26] nRCT 50/100 61/67.5 0.5 g Hb <80 g/l dabigatran B
Martin JG 2014 [25] RCT 25/25 63.9/63.0 2 g Hb <70 g/l Physical A
Van Elst CE 2013 [18] RCT 30/30 67.1/66.5 3 g Hb <100 g/l LMWH A
Wei 2014 [19] RCT 102/100 60.2/63.9 3 g Hb <90 g/l LMWH A
Wind 2014 [27] nRCT 70/1047 65/60 -- Hb <80 g/l -- C
Yin 2014 [20] RCT 30/30 50/53 2 g Hb < 70 g/l LMWH A
Yue C 2014 [21] RCT 52/49 60.9/63.7 3 g Hb <70 g/l LWMH A