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Table 2 Mean (SD) for VAS, KOOS, KQoL and functional tests at baseline and four and 12 weeks following final injection

From: Intra-articular injection of photo-activated platelet-rich plasma in patients with knee osteoarthritis: a double-blind, randomized controlled pilot study

  

PA-PRP

HA

  

Baseline (n = 11)

4 weeks (n = 11)

12 weeks (n = 10)

Baseline (n = 10)

4 weeks (n = 10)

12 weeks (n = 9)

Pain

VAS

48.09 (23.75)

19.64 (17.61)**

36.89 (25.42)

39.70 (21.90)

12.90 (14.06)

14.13 (9.30)

KOOS

Symptoms

48.70 (15.83)

57.14 (20.33)

57.86 (22.76)

62.14 (17.99)

61.07 (26.86)

80.16 (8.40)

 

Pain

57.07 (11.21)

71.47 (16.67)**

68.89 (15.76)*

70.00 (11.25)

67.22 (25.55)

79.32 (9.33)

 

Function

70.72 (13.64)

79.27 (15.08)

78.68 (15.87)

75.44 (12.42)

79.12 (28.63)

90.03 (7.31)**

 

Sport

31.82 (20.40)

40.46 (28.32)

41.00 (27.77)

47.00 (28.69)

46.50 (33.75)

64.44 (23.64)

 

QoL

30.11 (18.92)

40.89 (27.55)

38.75 (28.38)

41.87 (13.51)

42.50 (21.21)

54.86 (9.77)

KQoL

Physical

57.72 (18.35)

65.00 (18.14)*

68.83 (18.64)**

71.16 (14.91)

68.33 (27.54)

80.55 (13.46)

 

Activity

59.09 (23.33)

72.73 (16.79)

70.00 (22.23)

75.50 (15.71)

78.50 (29.16)

88.89 (7.41)

 

Emotional

46.97 (26.69)

58.71 (23.68)*

58.75 (29.49)**

58.75 (24.25)

67.08 (29.88)

75.00 (16.00)

Functional tests

Hops

46.64 (33.04)

57.64 (41.36)*

79.33 (34.17)**

55.50 (35.43)

51.50 (39.49)

79.25 (38.04)

 

Knee bends

19.45 (8.25)

22.27 (8.37)

31.44 (7.96)**

20.50 (13.23)

25.30 (16.60)

31.13 (15.63)

  1. Legend: VAS visual analogue score, KOOS knee osteoarthritis outcome score, QoL quality of life, KQoL knee quality of life, PA-PRP photo-activated platelet-rich plasma, HA hyaluronic acid
  2. *Indicates statistically significant (p < 0.05) improvement from baseline
  3. **Indicates statistically significant (p < 0.01) improvement from baseline