Skip to main content

Advertisement

Table 1 Characteristics of patient cohorts

From: Changing clinical patterns in rheumatoid arthritis management over two decades: sequential observational studies

Characteristic 1996-97 2001-03 2009-10 2012-14
  n = 189 n = 310 n = 304 n = 520*
Female gender, n (%) 140 (74 %) 237 (76 %) 244 (80 %) 413 (79 %)
Age, mean (SD) 59 (14) 60 (13) 59 (15) 58 (15)
Disease duration in years, median (IQR) 8 (13) 9 (10) 10 (9) 10 (9)
Any DMARD, n (%) 115 (61 %) 199 (64 %) 242 (80 %) 420 (87 %)
Combination DMARDs, n (%) 1 (1 %) 31 (10 %) 65 (21 %) 199 (41 %)
Biologic users, n (%) 0 11 (4 %) 53 (17 %) 155 (32 %)
Oral steroids, n (%) 23 (12 %) 70 (23 %) 30 (10 %) 56 (12 %)
DAS, mean (SD) 5.2 (1.6) 4.7 (1.6) 3.8 (1.5) 3.7 (1.6)
Tender joint count, mean (SD) 10.1 (9.2) 7.5 (7.3) 4.1 (5.6) 4.2 (6.2)
Swollen joint count, mean (SD) 7.1 (5.5) 4.8 (4.1) 2.9 (4.2) 1.5 (2.7)
Patient global, mean (SD) 50 (25) 50 (29) 40 (25) 35 (28)
ESR, mean (SD) 35 (26) 33 (27) 26 (21) 19 (21)
HAQ score, median (IQR) 1.30 (1.52) 1.52 (0.79) Not available 1.32 (0.84)
Pain, Mean (SD) 50 (24) 48 (28) Not available 44 (28)
Fatigue, Mean (SD) Not available 50 (28) Not available 51 (26)
  1. Legend: SD standard deviation, IQR interquartile range, *n = 484 for DMARD data