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Table 3 Association between change in cartilage thickness, and new or worsening meniscal extrusions, meniscal tears, and cartilage defects over 2.4 years; and change in joint space width over 5 years (n = 65)

From: Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population–based study

   Medial JSNa Lateral JSN
   Unadjusted Adjusted Unadjusted Adjusted
Tibial and femoral cartilage combined Tibial + femoral cartilage thickness R2 2.4 %, p = 0.21 R2 3.6 %, p = 0.14 R2 0.2 %, p = 0.71 R2 0.0 %, p = 0.91
New or worsening meniscal extrusion R2 1.5 %, p = 0.32 R2 0.4 %, p = 0.62 N/A N/A
Worsening meniscal tears R2 0.0 %, p = 0.99 R2 0.1 %, p = 0.78 R2 1.9 %, p = 0.27 R2 1.3 %, p = 0.38
  Worsening cartilage defects R2 2.1 %, p = 0.25 R2 1.1 %, p = 0.41 R2 1.0 %, p = 0.43 R2 0.9 %, p = 0.46
    Total R2 = 6.2 %   Total R2 = 2.3 %
Subgroup: cartilage measurement site
Tibial cartilage alone Tibial cartilage thickness R2 2.5 %, p = 0.33 R2 2.5 %, p = 0.21 R2 0.7 %, p = 0.52 R2 1.7 %, p = 0.30
New or worsening meniscal extrusion R2 1.5 %, p = 0.32 R2 0.8 %, p = 0.48 NA NA
  Worsening meniscal tears R2 0.0 %, p = 0.99 R2 0.2 %, p = 0.7 R2 1.9 %, p = 0.27 R2 1.3 %, p = 0.37
  Worsening cartilage defects R2 2.1 %, p = 0.25 R2 1.3 %, p = 0.37 R2 1.0 %, p = 0.43 R2 1 %, p = 0.43
    Total R2 = 5.1 %   Total R2 = 3.9 %
Femoral cartilage alone Femoral cartilage thickness R2 2.3 %, p = 0.22 R2 3.3 %, p = 0.15 R2 1.9 %, p = 0.27 R2 1.6 %, p = 0.31
New or worsening meniscal extrusion R2 1.5 %, p = 0.32 R2 0.3 %, p = 0.65 N/A N/A
  Worsening meniscal tears R2 0.0 %, p = 0.99 R2 0.1 %, p = 0.86 R2 0.4 %, p = 0.27 R2 1.6 %, p = 0.31
  Worsening cartilage defects R2 2.1 %, p = 0.25 R2 1.0 %, p = 0.44 R2 1.0 %, p = 0.43 R2 1.1 %, p = 0.40
    Total R2 = 5.9 %   Total R2 = 3.9 %
  1. Results obtained using linear regression
  2. aAdjusted for change in cartilage thickness, change in meniscal extrusion, change in meniscal tears or change in cartilage defects where applicable
  3. NA indicates not applicable (incidence of meniscal extrusion very low)
  4. Bold text indicates statistically significant result (p ≤ 0.05) (No associations were statistically significant)
  5. R2 for univariable models is the proportion of variance explained provided (R2) for the linear regression
  6. R2 for multivariable models is the proportion of variance explained for individual components of the multivariable model (semipartial R2)
  7. Total R2 is the proportion of variance explained for the entire multivariable model