Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population–based study

Table 3 Association between change in cartilage thickness, and new or worsening meniscal extrusions, meniscal tears, and cartilage defects over 2.4 years; and change in joint space width over 5 years (n = 65)

		Medial JSN^a		Lateral JSN
		Unadjusted	Adjusted	Unadjusted	Adjusted
Tibial and femoral cartilage combined	Tibial + femoral cartilage thickness	R² 2.4 %, p = 0.21	R² 3.6 %, p = 0.14	R² 0.2 %, p = 0.71	R² 0.0 %, p = 0.91
	New or worsening meniscal extrusion	R² 1.5 %, p = 0.32	R² 0.4 %, p = 0.62	N/A	N/A
	Worsening meniscal tears	R² 0.0 %, p = 0.99	R² 0.1 %, p = 0.78	R² 1.9 %, p = 0.27	R² 1.3 %, p = 0.38
	Worsening cartilage defects	R² 2.1 %, p = 0.25	R² 1.1 %, p = 0.41	R² 1.0 %, p = 0.43	R² 0.9 %, p = 0.46
			Total R² = 6.2 %		Total R² = 2.3 %
Subgroup: cartilage measurement site
Tibial cartilage alone	Tibial cartilage thickness	R² 2.5 %, p = 0.33	R² 2.5 %, p = 0.21	R² 0.7 %, p = 0.52	R² 1.7 %, p = 0.30
Tibial cartilage alone	New or worsening meniscal extrusion	R² 1.5 %, p = 0.32	R² 0.8 %, p = 0.48	NA	NA
	Worsening meniscal tears	R² 0.0 %, p = 0.99	R² 0.2 %, p = 0.7	R² 1.9 %, p = 0.27	R² 1.3 %, p = 0.37
	Worsening cartilage defects	R² 2.1 %, p = 0.25	R² 1.3 %, p = 0.37	R² 1.0 %, p = 0.43	R² 1 %, p = 0.43
			Total R² = 5.1 %		Total R² = 3.9 %
Femoral cartilage alone	Femoral cartilage thickness	R² 2.3 %, p = 0.22	R² 3.3 %, p = 0.15	R² 1.9 %, p = 0.27	R² 1.6 %, p = 0.31
Femoral cartilage alone	New or worsening meniscal extrusion	R² 1.5 %, p = 0.32	R² 0.3 %, p = 0.65	N/A	N/A
	Worsening meniscal tears	R² 0.0 %, p = 0.99	R² 0.1 %, p = 0.86	R² 0.4 %, p = 0.27	R² 1.6 %, p = 0.31
	Worsening cartilage defects	R² 2.1 %, p = 0.25	R² 1.0 %, p = 0.44	R² 1.0 %, p = 0.43	R² 1.1 %, p = 0.40
			Total R² = 5.9 %		Total R² = 3.9 %

Results obtained using linear regression
^aAdjusted for change in cartilage thickness, change in meniscal extrusion, change in meniscal tears or change in cartilage defects where applicable
NA indicates not applicable (incidence of meniscal extrusion very low)
Bold text indicates statistically significant result (p ≤ 0.05) (No associations were statistically significant)
R² for univariable models is the proportion of variance explained provided (R²) for the linear regression
R² for multivariable models is the proportion of variance explained for individual components of the multivariable model (semipartial R²)
Total R² is the proportion of variance explained for the entire multivariable model

ISSN: 1471-2474