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Table 5 Determinants for not increasing medication when patients have moderate/high disease activity

From: DAS steered therapy in clinical practice; cross-sectional results from the METEOR database

 

DAS > 2.4: medication is not increased vs medication is increased (n = 1.574 visits)a

ß

OR (95 % CI)

P-value

ESRa

0.00

1.00 (0.99–1.01)

0.86

SJCa

−0.02

0.99 (0.96–1.01)

0.20

VASpta

0.00

1.00 (0.99–1.01)

0.98

TJCa

0.05

1.05 (1.01–1.10)

<0.01

Actual druga

   

 DMARD monotherapy

1.19

3.28 (2.40–4.48)

<0.01

 MTX + bDMARD

0.66

1.93 (1.25–2.98)

<0.01

 DMARD combination therapy

0.12

1.12 (0.83–1.53)

0.46

 DMARD + prednisone

0.03

1.03 (0.67–1.57)

0.90

  1. aGEE binary logistic regression. Analysis is corrected for gender and age. ESR Erythrocyte Sedimentation Rate, SJC swollen joint count, TJC tender joint count, VasPtGlobal Patient Assessment of Global Disease Activity. Reference category ‘Actual drugs’ = other drugs