Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort

Table 4 Association between change in meniscal tears and knee structures on MRI over 8 years

	β (95 % CI)	β (95 % CI)	Risk ratio (95 % CI)
	Adjusted^a	Adjusted^a	Adjusted^a
Change in tears (site)	Cartilage volume loss	Change in BMLs	Change in meniscal extrusion
	Total tibiofemoral	Total tibiofemoral	Total knee
Total knee	−52 (−208, +102)	+0.41 (+0.29, +0.52)	N/A
	Medial tibiofemoral	Medial tibiofemoral	Medial meniscus
Total medial	−176 (−302, −49)	+0.33 (+0.22, +0.43)	1.53 (1.14, 2.03)
	Lateral tibiofemoral	Lateral tibiofemoral	Lateral meniscus
Total lateral	+143 (−731, +1018)	+0.26 (+0.10, +0.41)	N/A

Bold font denotes statistically significant (p = <0.05) results
(No significant offspring-control interaction at any site for the association between change in meniscal tears and change in BMLs)
Note: Not enough change in lateral meniscal extrusion for analysis due to lack of power
^aadjusted for age, sex, bmi, offspring-control status, cartilage volume loss, change in BMLs, cartilage defects and meniscal extrusion, and ROA at visit-1

ISSN: 1471-2474