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Table 2 Demographics, metal ion levels and frequencies of histological findings distributed by implant type

From: Diagnostic utility of joint fluid metal ion measurement for histopathological findings in metal-on-metal hip replacements

    THA Hip resurfacing p-value
Demographic variables Age Mean (SD) 60.5 years (8.4) 50.4 years (8.6) <.001
  Gender Males Females 72 69 12 10 .9
Metal ion levels Whole blood Median Co level (range) 11.9 ppb (1.1 – 139.9) 7.35 ppb (1 – 73) .03
  Median Cr level (range) 3.4 ppb (0.7 – 61.6) 3.85 ppb (0.8 – 31) .4
  Joint fluid Median Co level (range) 1291 ppb (36 – 19150) 271 ppb (40–5702) <.001
  Median Cr level (range) 903 ppb (24 – 39160) 390 ppb (4 ppb – 7698) .004
Histological observations Lymphocyte cuff thickness Absent 50 10 .3
  <0.25 mm 81 12  
  0.25 – 0.75 mm 10 -  
  Histiocyte sheet thickness Absent 4 - .4
  <1 mm 108 18
  1–2 mm 24 2
  >2 mm 5 2
  Surface necrosis Grade I 7 9 <.001
  Grade II 34 4
  Grade III 38 7
  Grade IV 62 2
  Particle load Grade 0 28 4 .6
  Grade 1 25 5
  Grade 2 37 3
  Grade 3 36 6
  Grade 4 15 4