Test | Lubricant [PRG4] (μg/mL), [HA] (mg/ml) | ||||
---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | |
1A: PRG4 low dose, HA (N = 4) | PBS | [PRG4] = 4.5 | [PRG4] = 45 | [PRG4] = 150 | SF |
[HA] = 3.33 | [HA] = 3.33 | [HA] = 3.33 | |||
1B: PRG4 high dose, HA (N = 6) | PBS | [PRG4] = 150 | [PRG4] = 450 | [PRG4] = 1500 | SF |
[HA] = 3.33 | [HA] = 3.33 | [HA] = 3.33 | |||
2A: PRG4 high, HA dose (N = 8) | PBS | [PRG4] = 450 | [PRG4] = 450 | [PRG4] = 450 | SF |
[HA] = 0.3 | [HA] = 1.0 | [HA] = 3.33 | |||
2B: PRG4 mid, HA dose (N = 4) | PBS | [PRG4] = 150 | [PRG4] = 150 | [PRG4] = 150 | SF |
[HA] = 0.3 | [HA] = 1.0 | [HA] = 3.33 | |||
2C: PRG4 low, HA dose (N = 4) | PBS | [PRG4] = 45 | [PRG4] = 45 | [PRG4] = 45 | SF |
[HA] = 0.3 | [HA] = 1.0 | [HA] = 3.33 | |||
3: R/A PRG4, HA (N = 8) | PBS | [PRG4] = 0 | R/A [PRG4] = 450 | [PRG4] = 450 | SF |
[HA] = 3.33 | [HA] = 3.33 | [HA] = 3.33 | |||
4: PRG4, cross-linked HA (N = 8) | PBS | [PRG4] = 0 | [PRG4] = 450 | SF | N/A |
[HYLAN G-F 20] = 3.33 | [HYLAN G-F 20] = 3.33 |  |