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Fig. 6 | BMC Musculoskeletal Disorders

Fig. 6

From: Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progression

Fig. 6

SOST expression in osteocytes. No difference in the percentage of SOST positive osteocytes in affected vertebrae between untreated and rSOST treated mice. a There was a decrease in SOST expression at unaffected joints, and a significant decrease in unaffected control mice compared to all other groups (* p <0.05). There was a significant increase in SOST positive cells in the unaffected joints of mice treated with rSOST in comparison to the unaffected joints of untreated control mice (# p < 0.05). b Example of SOST positive osteocytes (brown staining, red arrows). A negative osteocyte is also clearly visible (purple staining, blue arrow)

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