Fig. 6From: Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progressionSOST expression in osteocytes. No difference in the percentage of SOST positive osteocytes in affected vertebrae between untreated and rSOST treated mice. a There was a decrease in SOST expression at unaffected joints, and a significant decrease in unaffected control mice compared to all other groups (* p <0.05). There was a significant increase in SOST positive cells in the unaffected joints of mice treated with rSOST in comparison to the unaffected joints of untreated control mice (# p < 0.05). b Example of SOST positive osteocytes (brown staining, red arrows). A negative osteocyte is also clearly visible (purple staining, blue arrow)Back to article page