Fig. 1
From: The effects of zoledronate on the survival and function of human osteoblast-like cells
Zoledronate (ZOL) at the μM level presents a dose-dependently inhibitory effect on cellular proliferation of MG-63 and G-292 cells by inducing apoptosis. Sequential changes of (a) cell proliferation and (b) cell proliferation inhibition ratio of MG-63 and G-292 cells treated with ZOL for 48 h. Sequential changes of apoptotic cells of (c) MG-63 cells and (d) G-292 cells treated with ZOL for 48 h and 72 h. Data are mean ± standard deviation (SD). N = 3–5 for each experiment; *p < 0.05, **p < 0.001 (vs. the control group; ANOVA)