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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disorders

Fig. 1

Fluorescence micrographs of the initial scAAV serotype screening on day 8 of post-transduction. For the primary screening of the serotypes in NP cells, 1 x 105 NP cells were seeded and transduced with GFP packing scAAV serotypes at different viral genome copies per seeded cell (vg/c) and fluorescence micrographs were acquired up to 48 days. On day 8 of post-transduction scAAV2, scAAV3 and scAAV6 displayed the highest transduction efficiencies at a dose of 5000 vg/c. Original magnification: x 40

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