Table 2 Baseline demographic data of the groups either receiving or not receiving plasma exchange (PEX) as part of disease induction

Age (years)

61 ± 15

60 ± 17

0.81

Male / Female

26 / 20

27 / 31

-

ANCA status (%)

PR3+

26 (57)

25 (43)

0.67

MPO+

16 (35)

30 (52)

0.07

Negative

4 (8)

3 (5)

0.81

Diagnosis

GPA

26

25

0.67

MPA

12

29

0.02

ANCA- vasculitis

4

3

0.81

EGPA

3

1

0.32

Organ involvement

Number (%) of patients

Kidney

35 (76)

57 (98)

0.47

Lung

26 (46)

30 (52)

0.54

ENT

17 (37)

13 (22)

0.89

Nerve

14 (30)

8 (14)

0.03

Skin

10 (22)

8 (14)

0.26

Joints

7 (15)

11 (19)

0.65

Eye

4 (9)

5 (9)

0.96

Gastrointestinal

1 (2)

3 (5)

0.44

Indication for PEX

Number (%) of patients

Dialysis-requiring renal failure

-

20 (34)

Serum creatinine ≥500 μmol/l

-

12 (21)^a

Alveolar haemorrhage

-

9 (16)

Histologically significant renal disease

-

52 (90)

BVAS

17 (13 – 23)

29 (12 – 47)

0.01