Table 1 Clinical characteristics of Sjögren’s syndrome (SS) with HAM, whole HAM, SS with asymptomatic carrier and HTLV-I-seronegative SS
From: Reevaluation for clinical manifestations of HTLV-I-seropositive patients with Sjögren’s syndrome
HAM + SS (n = 10) (A) | AC + SS (n = 35) (B) | SS negative for anti-HTLV-I Ab (n = 125) (C) | p-value (A) vs. (B) | p-value (A) vs. (C) | p-value (B) vs. (C) | |
|---|---|---|---|---|---|---|
Age (yrs mean ± SD) | 64.0 ± 9.8 | 61.8 ± 12.4 | 58.1 ± 13.0 | 0.279 | 0.049 | 0.064 |
Sex (M/F) | 0/10 | 4/31 | 4/12 | 0.311 | 0.725 | 0.055 |
Dry eye (%) | 8/10 (80.0) | 23/33 (69.7) | 79/120 (65.8) | 0.421 | 0.296 | 0.423 |
Dry mouth (%) | 7/10 (70.0) | 29/33 (87.9) | 101/123 (82.1) | 0.96 | 0.908 | 0.309 |
MSGB grade 3 (%) | 6/10 (60.0) | 14/35 (40.0) | 44/125 (35.2) | 0.223 | 0.102 | 0.37 |
MSGB grade 4 (%) | 4/10 (40.0) | 19/35 (54.3) | 69/125 (55.2) | 0.331 | 0.274 | 0.615 |
Anti-nuclear antibody (%) | 4/10 (40.0) | 29/35 (82.9) | 110/125 (88.0) | 0.013 | <0.001 | 0.859 |
Centromere pattern in positive ANA (%) | 0/4 (0.0) | 2/29 (6.9) | 28/110 (25.4) | 0.769 | 0.318 | 0.021 |
Anti-SS-A/Ro or SS-B/La antibody (%) | 3/10 (30.0) | 23/35 (65.7) | 88/125 (70.4) | 0.044 | 0.014 | 0.772 |
Rheumatoid factor (%) | 3/5 (60.0) | 12/24 (50.0) | 48/90 (53.3) | 0.535 | 0.57 | 0.952 |
Serum IgG (mg/dL; mean ± SD) | 2349.2 ± 1015.5 | 2164.5 ± 1056.2 | 1922.3 ± 751.4 | 0.32 | 0.124 | 0.113 |
Schirmer’s test or Rose-Bengal test/Fluorescein (%) | 9/10 (90.0) | 28/31 (90.3) | 69/115 (60.0) | 0.754 | 0.055 | <0.001 |
Saxon test or sialography (%) | 8/10 (80.0) | 26/30 (86.7) | 101/116 (87.1) | 0.847 | 0.866 | 0.656 |