Table 1 Model inputs
From: Development and feasibility of a personalized, interactive risk calculator for knee osteoarthritis
| Input parameter | Possible values | |||
|---|---|---|---|---|
| Starting Age | 25 years through 45 years | |||
| Sex | Female | |||
| Male | ||||
| Race/ethnicity | White | |||
| Black | ||||
| Hispanic | ||||
| Obesity status | Obese | |||
| Non-obese | ||||
| Family history | Family history | |||
| No family history | ||||
| Occupational exposure | Present | |||
| Absent | ||||
| History of knee injury | Present | |||
| Absent | ||||
| OA Incidence (annual probability, %) | ||||
| Age Range | Non-obese male | Non-obese female | Obese Male | Obese Female |
| 25–34 | 0.12 | 0.14 | 0.25 | 0.38 |
| 35–44 | 0.13 | 0.15 | 0.25 | 0.41 |
| 45–54 | 0.23 | 0.28 | 0.47 | 0.62 |
| 55–64 | 0.41 | 0.46 | 0.76 | 1.19 |
| 65–74 | 0.24 | 0.31 | 0.46 | 0.55 |
| 75–84 | 0.21 | 0.22 | 0.36 | 0.48 |
| 85+ | 0.21 | 0.22 | 0.36 | 0.48 |
| OA Progression Estimates (annual probability, %) | ||||
| Male | Female | |||
| Progression from K-L 2 to K-L 3 (non-obese/obese) | 5.58/ 12.26 | 4.00/ 8.95 | ||
| Progression from K-L 3 to K-L 4 (non-obese/obese) | 1.29/ 2.94 | 1.95/ 4.27 | ||
| Risk Factors (multipliers for increased OA incidence, derived from Zhang et al. [33]) | ||||
| Knee injury | 2.39 | |||
| Family history of OA | 1.72 | |||
| Occupational risks | 1.28 | |||
