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Table 3 Perioperative irradiation and oral HO prophylaxis; HO = heterotopic ossification; Gy = Gray

From: Current therapeutic strategies of heterotopic ossification – a survey amongst orthopaedic and trauma departments in Germany

   Germany   
  University (trauma) University (orthopaedic) Non-university hospitals Total
Postoperative oral HO prophylaxis 100 % 81 % 86 % 88 %
Perioperative irradiation 90 % 96 % 91 % 92 %
Change in prophylaxis strategy 65 % 35 % 31 % 38 %
Diclofenac 0 % 25 % 30 % 17 %
Median dosage per day - 150 mg 150 mg 150 mg
Ibuprofen 11 % 25 % 10 % 13 %
Median dosage per day 1800 mg 1200 mg 1200 mg 1600 mg
Indomethacin 89 % 50 % 30 % 57 %
Median dosage per day 150 mg 150 mg 100 mg 100 mg
Etoricoxib 0 % - 20 % 9 %
Median dosage per day - - 90 mg 90 mg
Celecoxib 0 % - 10 % 4 %
Median dosage per day - - 400 mg 400 mg
Other -   - 0 %
Mean time of oral prophylaxis (days) 28 (min.14 – max.42) 42 (min.14 – max.98) 21 (min.7 – max.42) 30 (min.7 – max.98)
Pre-operative irradiation 75 % 86 % 90 % 83 %
Post-operative irradiation 25 % 14 % 10 % 17 %
Times of irradiation 1 1 1 1
Median dosage in Gy 7 7 7 7
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