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Table 2 Median values (minimum and maximum values) of O’Driscoll modified score parameters in cartilage explants

From: Experimentally induced cartilage degeneration treated by pulsed electromagnetic field stimulation; an in vitro study on bovine cartilage

Experimental time O’driscoll score parameters CTR IL1β PEMF IL1β + PEMF
24 h Safranin-O staining 2 (2–3) 1 (1–2)** 3 (2–3) 2 (2–2)§
Surface regularity 2 (2–3) 1 (1–2)** 3 (3–3) 2 (2–2)
Chondrocyte clustering 2 (1–2) 0.5 (0–1)** 2 (2–2) 1 (1–2)
Cellularity 2 (2–3) 1 (1–1)** 3 (2–3) 2 (1–2)§§
7 days Safranin-O staining 1 (1–2) 0 (0–1) 3 (2–3)°° 1 (1–2)§
Surface regularity 2 (1–3) 1 (0–1)** 3 (2–3) 1 (1–2)
Chondrocyte clustering 1 (1–1) 0 (0–1)**,a 2 (1–2)°° 1 (1–2)§
Cellularity 2 (1–2) 1 (0–1)** 2 (2–3) 1 (1–2)
21 days Safranin-O staining 1 (1–2) 0 (0–1) 2 (2–2)° 1 (1–1)§§
Surface regularity 2 (1–2) 1 (1–1)** 2 (2–2) 2 (1–2)§§, b
Chondrocyte clustering 1 (1–1) 0 (0–0)* 1 (1–1)b 1 (1–2)§
Cellularity 1 (1–1) 0 (0–1)**,a 1.5 (1–2) 1 (1–1)§§
  1. Control (CTR), exposed to PEMF (PEMF), treated with IL1β (IL1β) or treated with IL1β and stimulated with PEMF (IL1β + PEMF) explants. 24 h, 7 and 21 days (n = 6)
  2. Mann-Whitney U test: - Within each experimental time: IL1β versus CTR (*, p < 0.05; **, p < 0.005); PEMF versus CTR (°, p < 0.05; °°, p < 0.005); IL1β + PEMF versus IL1β (§, p < 0.05; §§, p < 0.005); Within each group: 7 days versus 24 h (a, p < 0.05); 21 days versus 7 days (a, p < 0.05; b, p < 0.005)
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