From: Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study
Right knee | Left knee | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Pain - | Pain + | Adjusted OR | 95 % CI | P values | Pain - | Pain + | Adjusted OR | 95 % CI | P values | |
Overall | ||||||||||
N | 1708 | 444 | 1721 | 431 | ||||||
Age, years | 70.8 ± 12.5 | 74.8 ± 10.4* | 1.04 | 1.03–1.035 | <0.0001 | 70.8 ± 12.5 | 74.7 ± 10.4* | 1.04 | 1.03–1.05 | <0.0001 |
BMI, kg/m2 | 22.5 ± 3.3 | 23.7 ± 3.7* | 1.13 | 1.10–1.17 | <0.0001 | 22.4 ± 3.3 | 23.8 ± 3.5* | 1.14 | 1.11–1.18 | <0.0001 |
Grip strength, kgf | 28.7 ± 9.7 | 25.5 ± 8.5* | 0.98 | 0.96–0.9996 | 0.0448 | 26.9 ± 9.5 | 23.8 ± 8.5* | 0.99 | 0.97–1.01 | 0.3464 |
Quadriceps muscle strength,kgf (5kgf increase) | 29.1 ± 11.2 | 23.9 ± 10.3* | 0.83 | 0.78–0.88 | <0.0001 | 27.9 ± 11.2 | 22.8 ± 10.2* | 0.84 | 0.79–0.89 | <0.0001 |
Weight bearing index, kgf/kg (0.1 kgf/kg increase) | 0.54 ± 0.20 | 0.44 ± 0.18* | 0.81 | 0.76–0.86 | <0.0001 | 0.52 ± 0.19 | 0.42 ± 0.19* | 0.83 | 0.77–0.88 | <0.0001 |
Lower limb muscle mass/height2,kg/m2 (0.1kg/m2 increase) | 2.59 ± 0.43 | 2.58 ± 0.43 | 0.97 | 0.92–1.02 | 0.2421 | 2.56 ± 0.43 | 2.56 ± 0.42 | 0.98 | 0.94–1.03 | 0.4326 |
Men | ||||||||||
N | 586 | 104 | 594 | 96 | ||||||
Age, years | 71.9 ± 12.5 | 76.1 ± 11.0* | 1.04 | 1.02–1.07 | <0.0001 | 72.0 ± 12.3 | 76.1 ± 11.7* | 1.04 | 1.02–1.07 | <0.0001 |
BMI, kg/m2 | 22.9 ± 3.2 | 23.9 ± 3.8* | 1.13 | 1.06–1.21 | 0.0002 | 22.9 ± 3.2 | 23.9 ± 4.0* | 1.13 | 1.06–1.21 | 0.0003 |
Grip strength, kgf | 37.5 ± 9.5 | 35.1 ± 9.0* | 0.98 | 0.95–1.01 | 0.3070 | 35.5 ± 9.0 | 33.3 ± 9.7* | 0.99 | 0.96–1.02 | 0.5031 |
Quadriceps muscle strength,kgf (5kgf increase) | 32.9 ± 12.5 | 26.4 ± 12.0* | 0.80 | 0.72–0.89 | <0.0001 | 31.4 ± 12.6 | 25.4 ± 11.4* | 0.82 | 0.91–1.23 | 0.0001 |
Weight bearing index, kgf/kg (0.1 kgf/kg increase) | 0.54 ± 0.20 | 0.42 ± 0.19* | 0.75 | 0.65–0.85 | <0.0001 | 0.52 ± 0.20 | 0.41 ± 0.18* | 0.78 | 0.68–0.89 | 0.0002 |
Lower limb muscle mass/height2, kg/m2 (0.1kg/m2 increase) | 2.95 ± 0.44 | 3.03 ± 0.47 | 1.01 | 0.92–1.10 | 0.8897 | 2.90 ± 0.44 | 2.97 ± 0.50 | 0.98 | 0.89–1.08 | 0.7281 |
Women | ||||||||||
N | 1122 | 340 | 1127 | 335 | ||||||
Age, years | 70.2 ± 12.5 | 74.4 ± 10.2* | 1.03 | 1.02–1.05 | <0.0001 | 70.2 ± 12.6 | 74.3 ± 10.0* | 1.03 | 1.02–1.05 | <0.0001 |
BMI, kg/m2 | 22.2 ± 3.3 | 23.7 ± 3.6* | 1.13 | 1.09–1.18 | <0.0001 | 22.2 ± 3.4 | 23.8 ± 3.4* | 1.15 | 1.11–1.19 | <0.0001 |
Grip strength, kgf | 24.1 ± 5.8 | 22.5 ± 5.8* | 0.98 | 0.95–1.004 | 0.1014 | 22.3 ± 6.0 | 21.1 ± 5.7* | 0.99 | 0.97–1.02 | 0.6256 |
Quadriceps muscle strength, kgf (5kgf increase) | 27.2 ± 9.9 | 23.2 ± 9.5* | 0.84 | 0.78–0.91 | <0.0001 | 26.1 ± 9.8 | 22.1 ± 9.7* | 0.85 | 0.79–0.91 | <0.0001 |
Weight bearing index, kgf/kg (0.1 kgf/kg increase) | 0.55 ± 0.20 | 0.45 ± 0.18* | 0.83 | 0.77–0.90 | <0.0001 | 0.52 ± 0.19 | 0.43 ± 0.19* | 0.84 | 0.78–0.91 | <0.0001 |
Lower limb muscle mass/height2,kg/m2 (0.1kg/m2 increase) | 2.41 ± 0.27 | 2.45 ± 0.32* | 0.95 | 0.89–1.02 | 0.1421 | 2.38 ± 0.29 | 2.44 ± 0.31* | 0.99 | 0.93–1.04 | 0.6166 |