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Table 2 Age, BMI, grip strength and lower limb muscle strength and muscle mass in subjects with and without knee pain

From: Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study

  Right knee Left knee
  Pain - Pain + Adjusted OR 95 % CI P values Pain - Pain + Adjusted OR 95 % CI P values
Overall           
 N 1708 444     1721 431    
 Age, years 70.8 ± 12.5 74.8 ± 10.4* 1.04 1.03–1.035 <0.0001 70.8 ± 12.5 74.7 ± 10.4* 1.04 1.03–1.05 <0.0001
 BMI, kg/m2 22.5 ± 3.3 23.7 ± 3.7* 1.13 1.10–1.17 <0.0001 22.4 ± 3.3 23.8 ± 3.5* 1.14 1.11–1.18 <0.0001
 Grip strength, kgf 28.7 ± 9.7 25.5 ± 8.5* 0.98 0.96–0.9996 0.0448 26.9 ± 9.5 23.8 ± 8.5* 0.99 0.97–1.01 0.3464
 Quadriceps muscle strength,kgf (5kgf increase) 29.1 ± 11.2 23.9 ± 10.3* 0.83 0.78–0.88 <0.0001 27.9 ± 11.2 22.8 ± 10.2* 0.84 0.79–0.89 <0.0001
Weight bearing index, kgf/kg (0.1 kgf/kg increase) 0.54 ± 0.20 0.44 ± 0.18* 0.81 0.76–0.86 <0.0001 0.52 ± 0.19 0.42 ± 0.19* 0.83 0.77–0.88 <0.0001
 Lower limb muscle mass/height2,kg/m2 (0.1kg/m2 increase) 2.59 ± 0.43 2.58 ± 0.43 0.97 0.92–1.02 0.2421 2.56 ± 0.43 2.56 ± 0.42 0.98 0.94–1.03 0.4326
Men           
 N 586 104     594 96    
 Age, years 71.9 ± 12.5 76.1 ± 11.0* 1.04 1.02–1.07 <0.0001 72.0 ± 12.3 76.1 ± 11.7* 1.04 1.02–1.07 <0.0001
 BMI, kg/m2 22.9 ± 3.2 23.9 ± 3.8* 1.13 1.06–1.21 0.0002 22.9 ± 3.2 23.9 ± 4.0* 1.13 1.06–1.21 0.0003
 Grip strength, kgf 37.5 ± 9.5 35.1 ± 9.0* 0.98 0.95–1.01 0.3070 35.5 ± 9.0 33.3 ± 9.7* 0.99 0.96–1.02 0.5031
 Quadriceps muscle strength,kgf (5kgf increase) 32.9 ± 12.5 26.4 ± 12.0* 0.80 0.72–0.89 <0.0001 31.4 ± 12.6 25.4 ± 11.4* 0.82 0.91–1.23 0.0001
Weight bearing index, kgf/kg (0.1 kgf/kg increase) 0.54 ± 0.20 0.42 ± 0.19* 0.75 0.65–0.85 <0.0001 0.52 ± 0.20 0.41 ± 0.18* 0.78 0.68–0.89 0.0002
 Lower limb muscle mass/height2, kg/m2 (0.1kg/m2 increase) 2.95 ± 0.44 3.03 ± 0.47 1.01 0.92–1.10 0.8897 2.90 ± 0.44 2.97 ± 0.50 0.98 0.89–1.08 0.7281
Women           
 N 1122 340     1127 335    
 Age, years 70.2 ± 12.5 74.4 ± 10.2* 1.03 1.02–1.05 <0.0001 70.2 ± 12.6 74.3 ± 10.0* 1.03 1.02–1.05 <0.0001
 BMI, kg/m2 22.2 ± 3.3 23.7 ± 3.6* 1.13 1.09–1.18 <0.0001 22.2 ± 3.4 23.8 ± 3.4* 1.15 1.11–1.19 <0.0001
 Grip strength, kgf 24.1 ± 5.8 22.5 ± 5.8* 0.98 0.95–1.004 0.1014 22.3 ± 6.0 21.1 ± 5.7* 0.99 0.97–1.02 0.6256
 Quadriceps muscle strength, kgf (5kgf increase) 27.2 ± 9.9 23.2 ± 9.5* 0.84 0.78–0.91 <0.0001 26.1 ± 9.8 22.1 ± 9.7* 0.85 0.79–0.91 <0.0001
Weight bearing index, kgf/kg (0.1 kgf/kg increase) 0.55 ± 0.20 0.45 ± 0.18* 0.83 0.77–0.90 <0.0001 0.52 ± 0.19 0.43 ± 0.19* 0.84 0.78–0.91 <0.0001
 Lower limb muscle mass/height2,kg/m2 (0.1kg/m2 increase) 2.41 ± 0.27 2.45 ± 0.32* 0.95 0.89–1.02 0.1421 2.38 ± 0.29 2.44 ± 0.31* 0.99 0.93–1.04 0.6166
  1. *p < 0.05 by non-paired student t test
  2. Adjusted ORs were calculated by multiple logistic regression analysis after adjustment for age, sex, and BMI overall and after adjustment for age and BMI in men and women
  3. BMI Body mass index, mJSW, Minimum joint space width