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Table 2 Baseline and follow-up means of the clinical scales, significance of intra-group changes and follow-up duration in months (NC = nucleated cells, SD = standard deviation, LEFS = lower extremity functional scale, NPS = numeric pain scale, IKDC = international knee documentation committee scale, P-values are for intra-group changes, improvement rating = percentage improvement rating scale)

From: A dose response analysis of a specific bone marrow concentrate treatment protocol for knee osteoarthritis

  NC ≤ 4 × 108 cells   NC > 4 × 108 cells  
Variable N Mean SD P-value N Mean SD P-value
NPS
Baseline 67 4 2   49 3.1 1.8  
Follow-up 67 3.1 2.5   49 1.7 2.1  
Change 67 −0.9 2.7 .006 49 −1.5 2.5 <.001
Follow-up duration 67 10.6 8.5   49 11 8.6  
LEFS
Baseline 57 48.8 13.9   37 50.7 13.9  
Follow-up 57 53.5 18.7   37 59.6 17  
Change 57 4.8 16.7 .001 37 8.9 15.3 .002
Follow-up duration 57 8.5 6.5   37 8.5 6.1  
IKDC
Baseline 25 45 16.1   22 55.9 16.6  
Follow-up 25 64.7 18   22 70.1 16.7  
Change 25 19.7 15.5 <.001 22 14.2 14.7 .004
Follow-up duration 25 6.3 7.5   22 5.7 3.5  
Improvement rating
Follow-up 137 47 37.1   103 48.3 41.3  
Follow-up duration 137 14.8 11.6   103 13.4 10.7