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Table 2 Baseline and follow-up means of the clinical scales, significance of intra-group changes and follow-up duration in months (NC = nucleated cells, SD = standard deviation, LEFS = lower extremity functional scale, NPS = numeric pain scale, IKDC = international knee documentation committee scale, P-values are for intra-group changes, improvement rating = percentage improvement rating scale)

From: A dose response analysis of a specific bone marrow concentrate treatment protocol for knee osteoarthritis

 

NC ≤ 4 × 108 cells

 

NC > 4 × 108 cells

 

Variable

N

Mean

SD

P-value

N

Mean

SD

P-value

NPS

Baseline

67

4

2

 

49

3.1

1.8

 

Follow-up

67

3.1

2.5

 

49

1.7

2.1

 

Change

67

−0.9

2.7

.006

49

−1.5

2.5

<.001

Follow-up duration

67

10.6

8.5

 

49

11

8.6

 

LEFS

Baseline

57

48.8

13.9

 

37

50.7

13.9

 

Follow-up

57

53.5

18.7

 

37

59.6

17

 

Change

57

4.8

16.7

.001

37

8.9

15.3

.002

Follow-up duration

57

8.5

6.5

 

37

8.5

6.1

 

IKDC

Baseline

25

45

16.1

 

22

55.9

16.6

 

Follow-up

25

64.7

18

 

22

70.1

16.7

 

Change

25

19.7

15.5

<.001

22

14.2

14.7

.004

Follow-up duration

25

6.3

7.5

 

22

5.7

3.5

 

Improvement rating

Follow-up

137

47

37.1

 

103

48.3

41.3

 

Follow-up duration

137

14.8

11.6

 

103

13.4

10.7

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