Development of a hematogenous implant-related infection in a rat model

Table 1 Experimental Design

	S. aureus CFUs	Survival (post inoculation)	n (femurs)/group/time point	Outcome measure
Experiment 1	0, 1×10⁴-1×10⁹	3-14 days	8	CFU bone, CFU wire
(bilateral)	0, 1×10⁴-1×10⁹	3-14 days	8	CFU bone, CFU wire
Experiment 2	1×10⁷	3-42 days	16	CFU bone, CFU wire, μCT, histology
(bilateral)	1×10⁷	3-42 days	16	CFU bone, CFU wire, μCT, histology
Experiment 3	1×10⁷	3-42 days	6	CFU bone, CFU wire
(unilateral)	1×10⁷	3-42 days	6	CFU bone, CFU wire

ISSN: 1471-2474